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A kind of Chinese medicinal composition for treating vasculitis

A composition and technology of vasculitis, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problem of unsatisfactory clinical treatment effect of vasculitis, and achieve guaranteed efficacy, good stability, and easy to use convenient effect

Active Publication Date: 2016-04-06
GUANGZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing treatment methods have limitations to varying degrees, and the clinical effect of treating vasculitis is not ideal

Method used

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  • A kind of Chinese medicinal composition for treating vasculitis
  • A kind of Chinese medicinal composition for treating vasculitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Weigh each component according to the following formula: Niu Dali 12g, Rehmannia glutinosa 12g, Angelica 6g, Achyranthes bidentata 6g, Caulis Spatholobus 12g, Hedyotis diffusa 6g, Jinniu 6g, and Two heads 6g.

[0037] Prepare Chinese medicine preparation according to the following steps:

[0038] 1. Take Niu Dali and Angelica sinensis, add 7 times the volume of the medicinal materials to soak in water for 0.5 hours, then distill with steam distillation for 1.5 hours to extract the volatile oil, and clathrate the obtained volatile oil with 4 times the amount of β-cyclodextrin to form volatile oil β- Cyclodextrin clathrate, the distilled aqueous solution is filtered and set aside, add two-headed sharps and Caulis Spatholobus to the medicinal residues, add 8 times the volume of 60% ethanol each time to extract 3 times, each time for 2 hours, filter After the filtrates are combined, the ethanol is recovered and concentrated under reduced pressure at 60°C to form a clear pas...

Embodiment 2

[0042] Weigh each component according to the following formula: Niu Dali 12g, Rehmannia glutinosa 12g, Angelica 6g, Achyranthes bidentata 6g, Caulis Spatholobus 12g, Hedyotis diffusa 6g, Jinniu 6g, and Two heads 6g.

[0043] Prepare Chinese medicine preparation according to the following steps:

[0044] 1. Take Niu Dali and Angelica sinensis, add 7 times the volume of the medicinal materials to soak in water for 0.5 hours, then distill with steam distillation for 1.5 hours to extract the volatile oil, and clathrate the obtained volatile oil with 4 times the amount of β-cyclodextrin to form volatile oil β- Cyclodextrin clathrate, the distilled aqueous solution is filtered and set aside, add two-headed sharps and Caulis Spatholobus to the medicinal residues, add 8 times the volume of 60% ethanol each time to extract 3 times, each time for 2 hours, filter After the filtrates are combined, the ethanol is recovered and concentrated under reduced pressure at 60°C to form a clear pas...

Embodiment 3

[0048] Weigh each component according to the following formula: Niu Dali 12g, Rehmannia glutinosa 12g, Angelica 6g, Achyranthes bidentata 6g, Caulis Spatholobus 12g, Hedyotis diffusa 6g, Jinniu 6g, and Two heads 6g.

[0049] Prepare Chinese medicine preparation according to the following steps:

[0050] 1. Take Niu Dali and Angelica sinensis, add 7 times the volume of the medicinal materials to soak in water for 0.5 hours, then distill with steam distillation for 1.5 hours to extract the volatile oil, and clathrate the obtained volatile oil with 4 times the amount of β-cyclodextrin to form volatile oil β- Cyclodextrin clathrate, the distilled aqueous solution is filtered and set aside, add two-headed sharps and Caulis Spatholobus to the medicinal residues, add 8 times the volume of 60% ethanol each time to extract 3 times, each time for 2 hours, filter After the filtrates are combined, the ethanol is recovered and concentrated under reduced pressure at 60°C to form a clear pas...

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Abstract

The invention provides a traditional Chinese medicine composition for treating angiitis. The composition comprises components such as beautiful millettia root, prepared rehmannia glutinosa, angelica sinensis, achyranthes root, caulis spatholobi, oldenlandia diffusa, zanthoxylum nitidum and anemonis raddeanae. Compared with a traditional Chinese medicine mixture which is frequently used in clinical application, the traditional Chinese medicine composition provided by the invention is good in stability, guaranteed in medicine effect and convenient to use since an extraction, purification and preparation process is combined with traditional Chinese medicine theories and clinical application requirements.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating vasculitis. Background technique [0002] Thromboangiitis obliterans (vasculitis) is one of the common types of peripheral arterial occlusive disease. It is an aseptic vascular inflammatory disease that occurs in small arteries and veins in the extremities, mainly involving small and medium blood vessels and nerves in the distal extremities. Especially in the blood vessels of the lower extremities, the vascular wall will produce periodic and non-suppurative inflammation, often accompanied by intraluminal thrombus, which can cause pain, ischemia, intermittent walking and other symptoms in the limbs, and in severe cases, it can cause limb ulcers or necrosis. Most patients are forced to amputate due to treatment failure and lose the ability to work, which seriously affects the quality of life of patients and brings ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61P9/14
Inventor 郭洁文钟世顺刘若轩
Owner GUANGZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE