Burn composition and application thereof in preparation of medicaments for preventing and treating burn scars

A composition and technology of Burnet, applied in the direction of drug combination, effective ingredients of hydroxyl compounds, plant raw materials, etc., can solve problems such as unsatisfactory clinical curative effect

Inactive Publication Date: 2014-07-02
高建
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, no matter what kind of treatment, the clinical efficacy is not ideal, and it brings huge economic burden to patients

Method used

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  • Burn composition and application thereof in preparation of medicaments for preventing and treating burn scars
  • Burn composition and application thereof in preparation of medicaments for preventing and treating burn scars
  • Burn composition and application thereof in preparation of medicaments for preventing and treating burn scars

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1: burn composition preparation

[0021] No. 1 ointment: take 500g each of rhubarb, burnet, gallnut, calamine, red stone, and yellow wax, 7.5kg of sesame oil, and 50g of borneol;

[0022] No. 2 ointment: take 500g each of rhubarb, burnet, gallnut, calamine, red stone, and yellow wax, 6kg of sesame oil, and 100g of borneol;

[0023] No. 3 ointment: take 500g each of rhubarb, burnet, gallnut, calamine, red stone, and yellow wax, 9kg of sesame oil, and 75g of borneol;

[0024] Preparation steps:

[0025] ①Grind Burnet, gallnut, calamine and red stone into medicinal powder and mix;

[0026] ② Heat the sesame oil to boiling;

[0027] ③ Add the yellow wax to the boiling sesame oil, stir until the yellow wax is completely melted, and stop heating;

[0028] ④ Gradually add the premixed medicinal powder to the sesame oil, stir and mix until the medicinal powder is evenly distributed;

[0029] ⑤ After cooling, add ice flakes, stir and mix well, that is.

Embodiment 2

[0030] Example 2: Animal Research of Burn Compositions in Treating Burn Scars

[0031] We conducted animal experiments on the burn composition No. 1 ointment prepared in Example 1, and the subjects of the animal experiments were rats with deep second-degree burns.

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PUM

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Abstract

The invention relates to the field of traditional Chinese medicine compositions, and discloses a burn composition and preparation and application thereof. By adopting the burn composition disclosed by the invention, the content of collagen I for a wound and hydroxyproline can be reduced, the HE (hematoxylin-eosin staining) result shows that incrassation of a wound corium layer can be relieved after intervention of the burn composition, the Masson staining result shows that the wound collagen structure is more complete than that of a model group after intervention of the burn composition, and the burn composition is reminded to play prevention and treatment effects on the burn scars. Therefore, the burn composition has a good prospect in the aspect of preparation of medicaments for preventing and treating the burn scars.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a burn composition, its preparation method and its application, especially the application of preventing and treating post-burn scar. Background technique [0002] Burns, especially in deep burns, often lead to the appearance of scars, which seriously affect the appearance and function of patients. With the improvement of burn treatment level, it is urgent and important to prevent and cure scar hyperplasia after burns. In recent years, research on scar has made some progress, but there is still no effective drug or technology that can effectively prevent and treat scar formation after burns. At present, there are mainly two types of treatment methods for scar hyperplasia after burns: surgical treatment and non-surgical treatment. Surgical treatment includes: scar reduction and fine suture after scar resection, dermabrasion, etc.; non-surgical tr...

Claims

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Application Information

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IPC IPC(8): A61K36/739A61K9/06A61P17/02A61K31/045A61K33/00A61K35/64
Inventor 高建苏涌
Owner 高建
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