Phase Control Method of Transcranial Focusing of High Intensity Ultrasound

Abstract

The invention relates to a phase control method for high-strength ultrasound transcranial focusing, in particular to control over amplitude values, initial phases and inter-set time delays of different trigger signal sets of a phase-controlled transducer. The problem that transcranial ultrasound causes injury to the skull and surrounding soft tissue. The method comprises the following steps that S1, the position of an intracranial target region is determined; S2, trigger sound intensities and the initial phases of control signals of all array elements of the phase-controlled transducer focusing on intracranial tissue are regulated and controlled; S3, according to distribution of a sonic pressure field and a temperature field formed by focusing on the intracranial target region, the positions of hotspots, where sound pressure and temperature rise are high, inside the skull are determined; S4, the sound intensities and the time delays of the control signals of the array elements of the phase-controlled transducer used for eliminating the hotpots inside the skull are worked out; S5, the array elements are excited, and whether the hotpots exist in the skull or not is verified. The method can be used for achieving transcranial focusing and reducing injury, caused by the transcranial ultrasound, to the skull, the brain tissue surrounding the skull and the scalp tissue surrounding the skull.

Description

technical field [0001] The invention relates to a phase control method for transcranial focusing of high-intensity ultrasound. By adjusting and controlling the excitation signal of each array element of a phase control array transducer, according to the steady-state sound pressure amplitude of the high sound pressure in the skull, that is, the hot spot And the vibration phase, set the excitation signal of each array element used to eliminate the hot spot and the time delay between different trigger signal groups, reduce the temperature rise of the hot spot in the skull, and achieve the purpose of avoiding the hot spot from causing damage to the skull and surrounding soft tissues. Background technique [0002] At present, focused ultrasound has been widely used in various fields such as engineering, agriculture, and medicine. High-intensity focused ultrasound technology has the advantages of good penetration performance, large penetration depth, and strong directivity. Especi...

AI Technical Summary

Problems solved by technology

However, the device uses a phase-controlled transducer with 1,000 array elements. The drive and control circuit of the transducer is complicated, the cost is high, and it is limited to the treatment of deep brain tissues with a small adjustable range; when treating superficial intracranial tissues, Formation of hot spots of elevated temperature within the skull that can cause damage to the skull and surrounding soft tissues

For spherical coronal-concave spherical phased transducers, although the phased transducers contain fewer array elements and the drive and control circuits are relatively simple, affected by their geometry, the sound beam emitted by this type of transducer is transparent. The acoustic window through the skull is small, which can easily cause ultrasonic energy deposition, causing damage to the skull and surrounding areas

At present, there is no spherical coronal concave spherical phased transducer and related treatment system available for transcranial therapy in the market

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