Vitamin E nano-microemulsion and preparation method thereof

Abstract

The invention belongs to the field of nano-microemulsions, and discloses a vitamin E nano-microemulsion. The vitamin E nano-microemulsion comprises the following components: 5wt%-15wt% of vitamin E, 10wt%-15wt% of Tween-65, 6wt%-12wt% of sodium stearyl lactate, 3wt%-5wt% of Span-80, 4wt%-9wt% of propylene glycol and the balance being water. A preparation method of the vitamin E nano-microemulsion comprises the processes of mixing and implementing vortex oscillation. The prepared vitamin E nano-microemulsion has the characteristics of high content of active ingredients, small grain size, high encapsulation efficiency and the like.

Description

technical field

[0001] The invention belongs to the field of microemulsions, and relates to a nano-microemulsion and a preparation method thereof, in particular to a nano-microemulsion of vitamin E and a method thereof. Background technique

[0002] Microemulsion is a thermodynamically stable, isotropic and transparent dispersion system formed by two immiscible liquids under the action of surfactant molecules. Microemulsion is a highly dispersed low-tension system composed of distilled water, oil, surfactant, co-surfactant, etc. in a certain proportion. Any change in the nature or quantity of any component in the components will affect the formation of microemulsion with nature. The selection of surfactant is the core of preparing microemulsion, commonly used surfactant is as follows: sodium dodecylbenzenesulfonate, sodium lauryl sulfate, nonionic surfactant such as Triton X-100 (nonylphenol Polyoxyethylene ether), Npn (nonylbenzene polyoxyethylene ether surfactant), Tween...