An anti-oxidant compound Chinese medicine extract isolate and preparation method thereof

An isolated, antioxidant technology, applied in pharmaceutical formulations, medical preparations containing active ingredients, antidote, etc., can solve the problems of ineffective free radical scavenging and weak antioxidant effect.

Active Publication Date: 2017-01-25
SUZHOU TIANLING CHINESE TRADITIONAL MEDICINE SLICE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Technical problem to be solved: There are many ingredients in conventional Chinese medicines that have antioxidant effects, but their antioxidant effects are weak and cannot effectively remove free radicals. It is necessary to extract and separate the ingredients of traditional Chinese medicines that have antioxidant effects, and then Carry out rational combination, to improve its antioxidant activity, therefore need a kind of antioxidation compound traditional Chinese medicine extract isolate and preparation method thereof

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] (1) Dry the purslane and pulverize it, then extract it with water, the extraction temperature is room temperature, the extraction time is 4 hours, and the weight of water is 4 times the weight of purslane. After extraction, take the supernatant, and put The water extract of purslane was obtained after the supernatant was concentrated in vacuum; (2) The mallow seeds were pulverized with a pulverizer, and then added with ethanol for extraction. The extraction temperature was 50°C, the extraction time was 40 minutes, and the ratio of solid to liquid was 1 : 7, after the extraction, the extract is filtered with a filter cloth, and after the filtration, the filtrate is vacuum-concentrated until no ethanol flows out, and the concentrate is collected, which is the ethanol extract of mallow seed; (3) the fishy smell after drying Grass is crushed, and then extracted with ethanol, the extraction temperature is 65°C, the extraction time is 30min, the ratio of solid to liquid is 1:3...

Embodiment 2

[0022](1) Dry the purslane and pulverize it, then extract it with water, the extraction temperature is room temperature, the extraction time is 4 hours, and the weight of water is 4 times the weight of purslane. After extraction, take the supernatant, and put The water extract of purslane was obtained after the supernatant was concentrated in vacuum; (2) The mallow seeds were pulverized with a pulverizer, and then added with ethanol for extraction. The extraction temperature was 50°C, the extraction time was 40 minutes, and the ratio of solid to liquid was 1 : 7, after the extraction, the extract is filtered with a filter cloth, and after the filtration, the filtrate is vacuum-concentrated until no ethanol flows out, and the concentrate is collected, which is the ethanol extract of mallow seed; (3) the fishy smell after drying Grass is crushed, and then extracted with ethanol, the extraction temperature is 65°C, the extraction time is 30min, the ratio of solid to liquid is 1:3,...

Embodiment 3

[0024] (1) Dry the purslane and pulverize it, then extract it with water, the extraction temperature is room temperature, the extraction time is 4 hours, and the weight of water is 4 times the weight of purslane. After extraction, take the supernatant, and put The water extract of purslane was obtained after the supernatant was concentrated in vacuum; (2) The mallow seeds were pulverized with a pulverizer, and then added with ethanol for extraction. The extraction temperature was 50°C, the extraction time was 40 minutes, and the ratio of solid to liquid was 1 : 7, after the extraction, the extract is filtered with a filter cloth, and after the filtration, the filtrate is vacuum-concentrated until no ethanol flows out, and the concentrate is collected, which is the ethanol extract of mallow seed; (3) the fishy smell after drying Grass is crushed, and then extracted with ethanol, the extraction temperature is 65°C, the extraction time is 30min, the ratio of solid to liquid is 1:3...

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicine, and discloses an anti-oxidation composite traditional Chinese medicine extraction isolate and a preparation method thereof. The anti-oxidation composite traditional Chinese medicine extraction isolate comprises the following extraction isolates by weight: 4-8 parts of a purslane water extract, 6-14 parts of a malva verticillata l ethanol extract, 2-5 parts of a heartleaf houttuynia herb ethanol extract, and 5-10 parts of an oriental arborvilae seed supercritical extract. The anti-oxidation composite traditional Chinese medicine extraction isolate preparation method comprises water extraction, alcohol extraction, supercritical extraction, column separation and other steps. The prepared composite traditional Chinese medicine extraction isolate has the significant superoxide anion free radical removing effect so as to improve the anti-oxidation performance of the traditional Chinese medicine.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a composite traditional Chinese medicine extraction isolate and a preparation method thereof, in particular to an antioxidant composite traditional Chinese medicine extraction isolate and a preparation method thereof. Background technique [0002] Free radicals are intermediate metabolites of various biochemical reactions in human life activities. They have high chemical activity and are the body's effective defense system. If they cannot be maintained at a certain level, they will affect the body's life activities. However, if there are too many free radicals and cannot be removed in time, they will attack the life macromolecules and various organelles in the body, causing various damages to the body at the molecular level, cell level, and tissue and organ level, and accelerate the aging process of the body And induce various diseases. [0003] Superoxide anion radical...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/78A61P39/06
CPCA61K36/14A61K36/185A61K36/74A61K36/78A61K2236/331A61K2236/333A61K2236/37A61K2300/00
Inventor 李建华
Owner SUZHOU TIANLING CHINESE TRADITIONAL MEDICINE SLICE
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