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A traditional Chinese medicine for treating esophageal cancer radical resection complicated with chylothorax and its preparation method

A technique of excision, chylothorax, applied in the field of medicine

Inactive Publication Date: 2017-06-16
滨州医学院附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there is no specific drug for the treatment of chylothorax after radical resection of esophageal cancer

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: the preparation of Chinese medicine composition granule of the present invention

[0029] Prescription: Tinglizi 150g, Morus alba 150g, Turmeric 100g, Trichosanthes 120g, Bupleurum 100g, White mustard seed 100g, Fructus aurantium 100g, Jujube 100g, Honeysuckle 120g, Scutellaria baicalensis 100g, Ophiopogon japonicus 100g, Radix ginseng 100g, Digupi 100g, licorice 60g.

[0030] Preparation:

[0031] (a) Decoct the 9 herbs of Tinglizi, Morus alba, Turmeric, Jujube, Scutellaria baicalensis, Ophiopogon japonicus, Adenophora, Digupi, and licorice with water 10 times the weight of the above-mentioned herbs twice, decocting each time For 1 hour, combine the two decoctions, concentrate under reduced pressure at 60°C to half the volume of the original decoction, pour it out and let it cool, refrigerate for 12 hours, filter, and concentrate the filtrate under reduced pressure at 60°C to a relative density of 1.25 ~1.28 clear cream;

[0032] (b) Soak Trichosanthes...

Embodiment 2

[0035] Embodiment 2: the preparation of Chinese medicine composition granule of the present invention

[0036] Prescription: Tinglizi 130g, Morus alba 170g, Turmeric 80g, Trichosanthes 140g, Bupleurum 80g, White mustard seed 120g, Citrus aurantium 80g, Jujube 120g, Honeysuckle 100g, Scutellaria baicalensis 120g, Ophiopogon japonicus 80g, Radix Ginseng 120g, Digupi 80g, licorice 80g.

[0037] Preparation:

[0038] (a) Decoct the 9 herbs of Tinglizi, Morus alba, Turmeric, Jujube, Scutellaria baicalensis, Ophiopogon japonicus, Adenophora, Digupi, and licorice with water 10 times the weight of the above-mentioned herbs twice, decocting each time For 1 hour, combine the two decoctions, concentrate under reduced pressure at 60°C to half the volume of the original decoction, pour it out and let it cool, refrigerate for 12 hours, filter, and concentrate the filtrate under reduced pressure at 60°C to a relative density of 1.25 ~1.28 clear cream;

[0039](b) Soak Trichosanthes rind, ...

Embodiment 3

[0042] Embodiment 3: the preparation of Chinese medicine composition granule of the present invention

[0043] Prescription: Tinglizi 170g, Morus alba 130g, Turmeric 120g, Gualou skin 100g, Bupleurum 120g, White mustard seed 80g, Fructus aurantium 120g, Jujube 80g, Honeysuckle 140g, Scutellaria baicalensis 80g, Ophiopogon japonicus 120g, Radix ginseng 80g, Digupi 120g, licorice 40g.

[0044] Preparation:

[0045] (a) Decoct the 9 herbs of Tinglizi, Morus alba, Turmeric, Jujube, Scutellaria baicalensis, Ophiopogon japonicus, Adenophora, Digupi, and licorice with water 10 times the weight of the above-mentioned herbs twice, decocting each time For 1 hour, combine the two decoctions, concentrate under reduced pressure at 60°C to half the volume of the original decoction, pour it out and let it cool, refrigerate for 12 hours, filter, and concentrate the filtrate under reduced pressure at 60°C to a relative density of 1.25 ~1.28 clear cream;

[0046] (b) Soak Trichosanthes rind,...

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PUM

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Abstract

The invention particularly relates to traditional Chinese medicine for treating complication chylothorax after esophageal cancer radical resection and a preparation method thereof and belongs to the technical field of medicine. The traditional Chinese medicine is prepared from the following traditional Chinese medicine materials in parts by weight: 11-19 parts of semen lepidii, 11-19 parts of white mulberry root-bark, 6-14 parts of turmeric, 8-16 parts of trichosanthes peel, 6-14 parts of radix bupleuri, 6-14 parts of semen brassicae, 6-14 parts of fructus aurantii, 6-14 parts of Chinese-date, 8-16 parts of honeysuckle, 6-14 parts of scutellaria baicalensis, 6-14 parts of radix ophiopogonis, 6-14 parts of adenophora stricta, 6-14 parts of cortex lycii radicis and 2-10 parts of liquorice. The traditional Chinese medicine for treating chylothorax after the esophageal cancer radical resection, provided by the invention, has the functions of eliminating pathogens from lung to expel fluid retention, managing qi, activating blood, eliminating phlegm and dredging collaterals. The traditional Chinese medicine is clinically used for treating the complication chylothorax after the esophageal cancer radical resection, the total effective rate is 94.6% and the cure rate is 83.78%.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine for treating chylothorax complicated by radical resection of esophageal cancer and a preparation method thereof. Background technique [0002] The occurrence of chylothorax after esophageal cancer surgery is a serious complication, and its incidence is reported to be about 0.4% to 2.6% in China. Chylothorax is one of the serious complications after resection of esophagus cancer. The loss of a large amount of body fluids, electrolytes, and nutrients will lead to rapid deterioration of the nutritional status of patients, and eventually failure and death. The main reason is that the thoracic duct or its branches were damaged, but it was not detected in time or properly treated during the operation, resulting in the leakage of chyle fluid after the operation, leading to chylothorax. In recent years, with the wide application of radical res...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P35/00A61P11/00A61P11/10
CPCA61K9/1623A61K36/23A61K36/233A61K36/31A61K36/34A61K36/342A61K36/355A61K36/428A61K36/484A61K36/539A61K36/605A61K36/725A61K36/752A61K36/815A61K36/8968A61K36/9066A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 李伟杨丽娟王玉玖董圣军封赞祥王锋吴恩刚
Owner 滨州医学院附属医院
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