Method and system for extracting abnormal parameters of brain

Abstract

The invention provides a method and system for extracting abnormal parameters of the brain. The method comprises the following steps: carrying out magnetic resonance diffusion tensor imaging and resting-state functional imaging scanning for the brain, and obtaining diffusion tensor data and resting-state functional data of the brain; building the structural connection network of the brain according to the diffusion tensor data; building the functional connection network of the brain according to the resting-state functional data; coupling the structural connection network with the functional connection network to obtain network coupling indexes; arraying and verifying the network coupling indexes and normal network coupling indexes, and extracting the parameters which are different from the normal network coupling indexes in the network coupling indexes. The method and the system are used for conveniently extracting the parameters sensitively reflecting the abnormity of the structure and the function of the brain.

Description

technical field [0001] The invention relates to the technical field of magnetic resonance imaging, in particular to a method and system for extracting abnormal brain parameters. Background technique [0002] Alzheimer's disease (AD) is a primary neurodegenerative disease, with neurofibrillary tangles and amyloid deposition as the main pathological basis, speech impairment and memory loss as the main features, and finally develops into intellectual loss , unable to talk and eat, limb contractures, etc., increased family and social burden. At present, there is no effective treatment for AD. If good preventive and therapeutic measures can be given in the early stage of AD, the number and incidence of AD can be effectively controlled. Therefore, how to detect and diagnose AD patients early is particularly important. [0003] At present, AD research using brain network methods can be divided into two categories: one is to use structural magnetic resonance imaging, diffusion mag...

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Problems solved by technology

[0004] By extracting the abnormal parameters of the brain, it is possible to diagnose whether the patient has AD in advance. At present, most of the AD research methods based on the brain network at home and abroad separate the function and structure of the brain for research, so that the traditional extraction of abnormal brain parameters It is difficult to extract parameters that sensitively reflect brain structure and function abnormalities

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