Dialysis concentrate for supplementing copper elements
A technology of concentrates and elements, which is applied in the direction of drug combination, drug delivery, and medical preparations containing active ingredients. The effect of guaranteeing the quality of life
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experiment example 1
[0028] Blood side: 5L of 706 generation plasma, add CuCl 2 2H 2 O 11.49mg (i.e. Cu 2+ The ion concentration is 13.4μmol / L);
[0029] Dialysate side: the formula of the dialysis concentrate is selected from the formula described in Example 1 in Table 3, and after dilution according to A:B:water=1:1.6:32.4, the ion concentration in the dialysate is as shown in Table 4:
[0030] Table 4: After the dialysis concentrate was diluted in Experimental Example 1, the ion concentration and pH value in the dialysate
[0031] ion
Na +
K +
Ca 2+
Mg 2+
Cl -
HCO 3 -
Cu 2+
pH
concentration
138mmol / L
2.0mmol / L
1.5mmol / L
0.5mmol / L
114mmol / L
27.36mmol / L
13.4μmol / L
7.0-8.0
[0032] After the simulated dialysis experiment example 1 was completed, the content of copper element in the 706 generation plasma and dialysate was detected by atomic absorption method, as shown in Table 5.
[0033] Table 5:...
experiment example 2
[0036] Blood side: 5L of 706 generation plasma, add CuCl 2 2H 2 O 11.49mg (i.e. Cu 2+ The ion concentration is 13.4μmol / L);
[0037] Dialysate side: the formula of the dialysis concentrate is selected from the formula described in Example 2 in Table 3, and after dilution according to A:B:water=1:1.6:32.4, the ion concentration of the dialysate is as shown in Table 6:
[0038] Table 6: After the dialysis concentrate was diluted in Experimental Example 2, the ion concentration and pH value in the dialysate
[0039] ion
Na +
K +
Ca 2+
Mg 2+
Cl -
HCO 3 -
Cu 2+
pH
concentration
138mmol / L
2.0mmol / L
1.5mmol / L
0.5mmol / L
114mmol / L
27.36mmol / L
6.7μmol / l
7.0-8.0
[0040] After the simulated dialysis experiment example 2 was completed, the content of copper element in the 706 generation plasma and dialysate was detected by atomic absorption method, as shown in Table 7.
[0041] Table 7: ...
experiment example 3
[0044] Blood side: 5L of 706 generation plasma, add CuCl 2 2H 2 O 11.49mg (i.e. Cu 2+ The ion concentration is 13.4μmol / L);
[0045] Dialysate side: the formula of the dialysis concentrate is selected from the formula described in Example 3 in Table 3, and after dilution according to A:B:water=1:1.6:32.4, the ion concentration of the dialysate is as shown in Table 8:
[0046] Table 8: After the dialysis concentrate was diluted in Experimental Example 3, the ion concentration and pH value in the dialysate
[0047] ion
Na +
K +
Ca 2+
Mg 2+
Cl -
HCO 3 -
Cu 2+
pH
concentration
138mmol / L
2.0mmol / L
1.5mmol / L
0.5mmol / L
114mmol / L
27.36mmol / L
3.3μmol / l
7.0-8.0
[0048] After the simulated dialysis experiment example 3 was completed, the content of copper element in the 706 generation plasma and dialysate was detected by atomic absorption method, as shown in Table 9.
[0049] Table 9: ...
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