Citicoline Sodium injection pharmaceutical composition and preparation method thereof

A technology of citicoline sodium and injection, which is applied in the field of citicoline sodium injection pharmaceutical composition and preparation method, and can solve problems such as product instability, increased dosage, and increased related substances
CN104490771AInactive Publication Date: 2015-04-08CHENGDU TIANTAISHAN PHARMA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CHENGDU TIANTAISHAN PHARMA
Publication Date
2015-04-08
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a citicoline sodium injection pharmaceutical composition and a preparation method thereof. Particularly, the invention belongs to the technical field of medicines, relates to a pharmaceutical composition for treating consciousness disturbance caused by acute craniocerebral trauma and brain surgery and particularly relates to an injection pharmaceutical composition for treating consciousness disturbance caused by acute craniocerebral trauma and brain surgery. More particularly, the invention relates to the citicoline sodium injection pharmaceutical composition and a preparation method of citicoline sodium injection. The citicoline sodium injection comprises citicoline sodium and injection water, wherein the injection water serves as a solvent, and the concentration of citicoline sodium is 0.01g / ml-1g / ml. The citicoline sodium injection has excellent pharmaceutical properties explained in the specification.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, and relates to a pharmaceutical composition for treating disturbance of consciousness caused by acute craniocerebral trauma and brain surgery, in particular to a pharmaceutical composition for treating disturbance of consciousness caused by acute craniocerebral trauma and brain surgery The injection pharmaceutical composition, more particularly relates to a kind of citicoline sodium injection pharmaceutical composition, the present invention also relates to the preparation method of this injection. Background technique

[0002] Citicoline Sodium (Citicoline Sodium) is the monosodium salt of choline cytosine nucleoside diphosphate, its molecular formula is C14H25N4NaO11P2, its molecular weight is 510.31, and its chemical structure is as follows:

[0003]

[0004] Citicoline sodium is white crystal or crystalline powder; odorless. Citicoline Sodium is easily soluble in water, but insoluble in ...

Claims

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