Tree peony bark medicinal material based on activity screening and preparation detecting method

A detection method and technology of Cortex Moutan, applied in the field of Chinese medicine research methodology, can solve problems such as inability to objectively and accurately reflect the quality of Cortex Moutan medicinal materials.
CN104535677AInactive Publication Date: 2015-04-22JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
Publication Date
2015-04-22
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a method for controlling quality of multiple components of a tree peony bark medicinal material, an intermediate and a preparation product. The method comprises the following steps: screening out components and grouping the components through a cell membrane solid-phase chromatography technology and a glycosylation incubation system; on the basis of determining the six main components which are oxypaeoniflorin, paeoniflorin, trigalloyl glucose, pentagalloyl glucose, benzoyl-paeoniflorin and paeonol by combining cluster analysis with main component analysis, establishing a content synchronous measurement method for oxypaeoniflorin, paeoniflorin, trigalloyl glucose, pentagalloyl glucose, benzoyl-paeoniflorin and paeonol in the tree peony bark medicinal material, a tree peony bark extract intermediate and the tree peony bark preparation product by adopting the same liquid-phase chromatographic condition, and determining the component composition structure ratio range as follows: (1.3-1.5):(10.4-13.9):0.5:(2.7-3.5):(1.0-1.2):(14.9-16.1).
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Description

technical field

[0001] The invention relates to a method for detecting cortex moutan medicinal materials and preparations based on activity screening, and belongs to the field of research methodology of traditional Chinese medicine. Background technique

[0002] At present, the quality control method of Chinese medicinal materials, intermediates and preparations at home and abroad is to establish a qualitative and quantitative analysis method for one or two active ingredients (main components) in Chinese medicine on the basis of chemical composition research, and then control the quality of Chinese medicine. . However, this quality control method fails to reflect the overall characteristics of traditional Chinese medicine, and fails to provide evidence related to these quality control indicators and drug efficacy. What is more worthy of attention is that the quality control of these ingredients is not as high as possible, but different ingredients. It should be controlled w...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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