Application of clove-ephedra patch for dyspnea due to cold and detection method for clove-ephedra patch

A technology of sesame and clove, which is applied in the field of application and detection of Xiangma Hanchuan Patch, can solve the problems that children are not easy to accept, difficult to be accepted, difficult to cooperate, etc., to achieve simple preparation, curative effect when used alone, and low cost Effect

Active Publication Date: 2015-07-01
XIANGYU PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Acupuncture and moxibustion therapy for asthma is difficult for children to accept and cooperate with
Some people u

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Xiangma Hanchuan Patch, which is prepared from the raw materials in the following weight ratio:

[0028] 80 parts of cloves, 80 parts of ephedra, 50 parts of schisandra, 50 parts of white mustard seeds, 40 parts of astragalus,

[0029] 40 parts of Sage Grass, 40 parts of Plantago, 35 parts of Fritillaria, 35 parts of Dannanxing, 35 parts of Houttuynia cordata,

[0030] 35 parts of dandelion, 35 parts of poria cocos, 35 parts of acacia bark, 30 parts of Bupleurum, 30 parts of frankincense,

[0031] 30 parts of perilla leaf, 30 parts of Cyperus cyperi, 30 parts of cassia twig, 25 parts of black plum, 25 parts of Andrographis paniculata,

[0032] 20 parts of ginger, 20 parts of coltsfoot, 20 parts of Fangfeng, 20 parts of Yanhusuo, 20 parts of myrrh,

[0033] 15 parts of mulberry leaves, 15 parts of red peony.

[0034] Its preparation method is as follows:

[0035] 1) Take each bulk drug and set aside;

[0036] 2) Take cloves, ephedra, schisandra, psyllium, dandelion,...

Embodiment 2

[0041] Animal experiment

[0042] Acute toxicity test: the Xiangma Hanchuan plaster prepared in Example 1 is applied to the complete and damaged skin of rabbits with 6 times the amount of external plastering for children each time. There is no irritation after repeated administration, and there is no allergic reaction to the skin of guinea pigs. No toxic side effects were found.

[0043] Long-term toxicity test: the Xiangma Hanchuan plaster prepared in embodiment 1 is respectively pasted on the rabbit back (both lung projection back) of depilation with 2 times, 5 times, and 10 times of the amount of externally pasted for children. 4 hours each time, once a day, for 2 consecutive weeks. Observation of its blood picture, lung, liver and kidney function showed no toxic effects; no toxic damage was found in the heart, liver, spleen, lung, kidney and other organs by pathological section. Therefore, it is suggested that the clinically recommended dosage is safe to use.

[0044] Bot...

Embodiment 3

[0048] clinical information

[0049] A total of 113 outpatients in this group were selected for treatment, aged between 3 and 12 years old, with an average age of 6.8 years; they were randomly divided into two groups, namely, 57 cases in the experimental group and 56 cases in the control group. , course of disease and disease distribution were not statistically significant (P>0.05).

[0050] Diagnostic criteria for asthma:

[0051] 1. Recurrent episodes of wheezing, shortness of breath, chest tightness or cough are mostly related to exposure to allergens, cold air, physical and chemical stimuli, viral upper respiratory tract infections, exercise, etc.; Diffuse wheezing mainly in the expiratory phase, with protracted expiratory phase; 3. The above symptoms and signs can be relieved by treatment or relieved spontaneously; 4. Other diseases except wheezing, shortness of breath, chest tightness and cough; 5. 1. Those with atypical clinical manifestations (such as no obvious whee...

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Abstract

The invention relates to an application of a clove-ephedra patch for dyspnea due to cold. The clove-ephedra patch is prepared from the following raw materials: clove, ephedra, schisandra chinensis, sinapis alba, astragalus membranaceus, affine cudweed, semen plantaginis, thunberg fritillary bulb, bile arisaema, houttuynia cordata, dandelion, poria cocos, cortex albiziae, radix bupleuri, olibanum, perilla leaf, rhizoma cyperi, cassia twig, dark plum, kalmegh, fresh ginger, flos farfarae, divaricate saposhnikovia root, rhizoma corydalis, myrrh, mulberry leaf and red peony root. All the components interact mutually and are matched very well to coordinate efficiency; the cost is low; and through clinical verification, the clove-ephedra patch has a good treatment effect on infantile asthma.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to the application of Xiangma Hanchuan Plaster and its detection method. Background technique [0002] Asthma and bronchitis in children are common and frequently-occurring diseases in pediatric clinics, which not only endanger children's health, but also cause huge economic burdens to families and society. According to data reports, the prevalence rate of childhood asthma in my country is 0.5% to 2%, and it is as high as 5% in some places. There are about 20 to 40 million children in the country. Modern medicine believes that bronchial asthma is a respiratory hyperresponsive disease caused by hypersensitivity. In terms of drug treatment, it is emphasized that according to the needs of the condition, in addition to the use of antispasmodic and antiasthmatic drugs (symptomatic treatment), anti-airway allergic inflammation drugs should also be used i...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/70A61P11/06
Inventor 林凡儒王世礼李宁刘倩杜玲杰
Owner XIANGYU PHARMA
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