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Method and device for constructing protein classification model

A technology for classification models and construction methods, which is applied in the field of biology, can solve the problems of large noise interference and low precision of prediction methods, and achieve the effect of improving the screening ability

Inactive Publication Date: 2018-07-13
NAT UNIV OF DEFENSE TECH
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

[0009] The invention provides a method and device for constructing a protein classification model to solve the technical problems of low prediction method accuracy and large noise interference in the prior art

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  • Method and device for constructing protein classification model
  • Method and device for constructing protein classification model
  • Method and device for constructing protein classification model

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Embodiment Construction

[0034] The embodiments of the present invention will be described in detail below with reference to the accompanying drawings, but the present invention can be implemented in many different ways defined and covered by the claims.

[0035] In order to enable those skilled in the art to better understand the solutions of the present invention, the following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only It is an embodiment of a part of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0036] It should be noted that the terms "first" and "second" in the description and claims of the pre...

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Abstract

The present invention provides a method and device for constructing a protein classification model. The method for constructing a protein classification model includes: obtaining classification characteristics of tissue-expressed proteins; obtaining a prediction model of tissue-specific protein expression according to the classification characteristics; and classifying proteins according to the prediction model. In the case of collecting gene expression data, the method provided by the present invention also collects other characteristics of the gene expression protein, and classifies it significantly after constructing a negative set and a positive set, and can obtain the prediction result by Bayesian classifier Reliability scoring, and comprehensive annotation information.

Description

technical field [0001] The invention relates to the field of biology, in particular to a method and device for constructing a protein classification model. Background technique [0002] Although all the genes contained in a cell are the same, in different tissues, cells express only a subset of genes. The study of proteins specifically expressed in various tissues plays an important role in understanding the functions and mechanisms of proteins. Existing research methods mainly examine whether each gene is expressed in a certain tissue based on the expression data of the gene in each cell or tissue, such as a gene chip. If a gene is only expressed in one tissue or one cell type, the gene is defined as a tissue-specific gene, and its corresponding protein is a tissue-specific expressed protein. A gene that is expressed in most tissues is defined as a widely expressed gene, and the protein corresponding to the gene is a widely expressed protein. At the same time, researcher...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06F19/12G06F19/18
Inventor 刘伟孙志强宫二玲
Owner NAT UNIV OF DEFENSE TECH