A kind of preparation method of probiotic microcapsule for external use

Abstract

The invention discloses an external probiotics microcapsule preparation method. By making full use of the synergistic effect of plant extracts and probiotics, on one hand, survival rate and entrapment rate are cooperatively increased; on the other hand, the plant extracts have a further effect on skin care. The external probiotics microcapsule preparation method includes the steps: (1) respectively inoculating freeze-dried powder of bifidobacteria, lactobacillus acidophilus and lactobacillus rhamnosus into a triangular flask for activating treatment, enlarging fermentation cultivation and mixing fermentation liquor of the bifidobacteria, the lactobacillus acidophilus and the lactobacillus rhamnosus according to the volume ratio 3:3:4 to obtain bacterial suspension; (2) preparing nostoc commune extracts; (3) adding Tween-80 for emulsion into the bacterial suspension, the nostoc commune extracts and sodium alginate solution, curing the bacterial suspension, the nostoc commune extracts and the sodium alginate solution, filtering the bacterial suspension, the nostoc commune extracts and the sodium alginate solution by gauze after a wet capsule is formed, and flushing the wet capsule for three times by normal saline.

Description

technical field

[0001] The invention belongs to the technical field of biomedicine, and in particular relates to a preparation method of probiotic microcapsules for external use. Background technique

[0002] In recent years, many bacterial fermentation products have been applied to cosmetics and external skin applications, such as bifid yeast extract, sake yeast extract, etc. Probiotic cosmetics have revolutionized the entire industry. Its appearance makes the concept of natural, healthy and organic cosmetics more popular. Probiotic cosmetics can be roughly divided into three categories: one is probiotic yogurt cosmetics, such as facial masks made with probiotic yogurt. The second is the active extract of probiotic fermentation broth, and the third is to directly add sufficient probiotics and prebiotics to cosmetics. Each of the three types of products has its own characteristics. First of all, probiotic yogurt is a good beauty product. It has more nutrients (a variety ...

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