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Composite membrane and soft housing leukocyte filter using the same

A white blood cell and filter technology, applied in blood filtration, membrane technology, suction equipment, etc., can solve time-consuming and labor-intensive problems, achieve strong adsorption capacity, prevent breakage or falling off, and improve the fixing effect

Inactive Publication Date: 2015-10-28
NANJING SHUANGWEI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this product uses a hard-shell filter. In clinical applications, the whole blood is first filtered, then the filter is removed by heat sealing, and then the blood components are separated by centrifugation, which is time-consuming and laborious.
Moreover, most of the blood components are now prepared with red blood cell suspensions that remove leukocytes, which cannot be achieved with existing hard shell filters.

Method used

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  • Composite membrane and soft housing leukocyte filter using the same
  • Composite membrane and soft housing leukocyte filter using the same
  • Composite membrane and soft housing leukocyte filter using the same

Examples

Experimental program
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Embodiment 1

[0022] Such as figure 1 , figure 2 As shown, a soft-shell leukocyte filter A of a composite membrane filter medium includes a filter membrane assembly, an outer membrane 21 before a PVC filter, an outer membrane 22 after a PVC filter, and the outer membrane 21 before a PVC filter and the outer membrane 22 after a PVC filter pass through Hot pressing seals the filter membrane assembly from both sides.

[0023] The filter membrane assembly includes an inlet conduit 31 and an outlet conduit 41 arranged on the surface of the soft shell filter, and a composite filter membrane 10 arranged between two PVC outer membranes to form a pre-filter cavity 30 and a filter cavity 40 . The inlet conduit 31 and the outlet conduit 41 are arranged parallel to each other in opposite directions, which facilitates hanging online blood filtration. The pre-filtered liquid chamber 30 communicates with the inlet conduit 31 ; the filtered liquid chamber 40 communicates with the outlet conduit 41 . Th...

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PUM

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Abstract

The invention discloses a composite membrane and a soft housing leukocyte filter using the same. The composite membrane a composite filtering membrane is wrapped in PVC membranes and includes a combination of glass fiber membranes and a polyester fiber membranes. The composite filtering membrane achieves a filtering rate of leukocytes from blood and blood platelets in the blood components exceeding 99.99 percent, thus meeting the EU standards. Further optimization of the size and composition constitution method of the composite filtering membrane can realize the mechanical stability and thermostability of the glass fiber membranes, and guarantee the quality and effects of the use of the composite filtering membrane.

Description

technical field [0001] The invention relates to a composite membrane soft-shell leukocyte filter in the field of blood purification, in particular to a structure that adopts an organic membrane and an inorganic membrane composite coating to realize efficient assembly of the inorganic membrane in the filter for online blood filtration before and after centrifugation . Background technique [0002] Modern science has found that white blood cells will release a variety of cytokines during storage, causing allergic-like reactions in patients. White blood cells will undergo apoptosis and produce white blood cell fragments after being stored in anticoagulated whole blood for 72 hours. The US FDA recommends filtering white blood cells within 72 hours after blood collection, which is called Pre-storage Filtration. In the leukocyte filtration device used to filter blood and its components, most of the filter housings are hard-shell filters of ABS and PC injection molding parts. Gene...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/34B01D69/12
CPCA61M1/3406A61M1/3417A61M1/3482A61M1/3496B01D69/12
Inventor 谢伟娟钦湘孙号丁玉兰肖国锋
Owner NANJING SHUANGWEI BIOTECH