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Rotary type tubular tissue biological 3D printing device and method thereof

A tissue biology and 3D printing technology, applied in the field of tissue engineering technology and biological 3D printing, can solve the problems of easy collapse of printing length and difficult to form, and achieve the effect of controllable printing length, solving difficult forming and reducing manufacturing cost.

Inactive Publication Date: 2015-10-28
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] With the advancement of tissue engineering research, the research work has gradually extended to large soft tissues, internal organs and tubular tissues and organs, especially for tubular tissues and organs such as trachea, larynx and intestinal tract, etc., because these tissues and organs often contain A variety of cells and biological materials, and the molding shape is cylindrical, the printing length is slightly longer, it is easy to collapse and difficult to form, and different cells or materials have specific spatial arrangements, so the above technical limitations are more prominent

Method used

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  • Rotary type tubular tissue biological 3D printing device and method thereof
  • Rotary type tubular tissue biological 3D printing device and method thereof
  • Rotary type tubular tissue biological 3D printing device and method thereof

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Embodiment Construction

[0028] The specific structure, working principle and working process content of the present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0029] Such as Figure 1-4 As shown, a rotary tubular tissue biological 3D printing molding device includes a frame bed 1, an air source 2, a lifting mechanism assembly 3, a controller 4, a rotating connection tray assembly 5, a columnar bracket 6, and a nozzle drive assembly; The lower part of the lifting mechanism assembly 3 is installed and fixed with the inner lower plate of the frame bed body 1, and the upper part is connected with the lower part of the rotating connecting tray assembly 5, which can drive the rotating connecting tray assembly 5 to move up and down; the upper part of the rotating connecting tray assembly 5 is fixedly placed on a column Bracket 6, the middle part passes through the middle through hole of the table top of the frame bed body 1, and the lower part ...

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Abstract

The invention discloses a rotary type tubular tissue biological 3D printing device and a method thereof. The rotary type tubular tissue biological 3D printing device comprises a rack bed body, an air source, a lifting mechanism assembly, a controller, a rotary connecting tray assembly, a spray head drive assembly and the like, wherein under the control of the controller, an air pressure spray head moves to the position of a cylindrical bracket; an air source is used for supplying air to the air pressure spray head by virtue of an air tube for pressing out a biological material, and a motor b of the rotary connecting tray assembly drives a rotary tray to carry out rotary motion; after the rotary tray rotates by one circle, pneumatic spray heads move by a specified distance in a radial direction to print a next position. When one layer is printed, a motor a drives the lifting mechanism assembly to control the rotary connecting tray assembly to move downwards, so that printing of a tubular tissue is realized. By increasing the group number of the pneumatic spray heads, the printing of the tubular tissue with a heterostructure can be realized. The rotary type tubular tissue biological 3D printing device is simple and delicate in structural concept, liable to realize automatic control, and capable of printing various materials, so that the printing efficiency is improved; and the problem that the tubular tissue is not liable to print and form is effectively solved.

Description

technical field [0001] The invention relates to a rotary tubular tissue biological 3D printing forming device and a method thereof, which are used for printing cells and biological materials, and belong to the field of tissue engineering technology and biological 3D printing. Background technique [0002] For the treatment of damaged large soft tissues and internal organs, human tissue and organ transplantation is an extremely effective treatment method. However, due to the shortage of organ donor sources, immune rejection and other problems, there are insurmountable difficulties in the practical application of organ transplantation. The proposal of tissue engineering has opened up a new way to solve the above problems. Tissue engineering is to attach living cells to biomaterial matrices or prepared scaffolds by a certain method to construct functional tissue substitutes. [0003] With the advancement of tissue engineering research, the research work has gradually extended...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B29C67/00B33Y30/00B33Y10/00
Inventor 张斌张刚马艳双马吉恩杨华勇
Owner ZHEJIANG UNIV
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