Anti-allergic compound polysaccharide composition, preparation method and application thereof

Abstract

The invention relates to an anti-allergic compound polysaccharide composition which is prepared from following components, by weight: 10-90 parts of astragalus membranaceus, 10-90 parts of cortex albiziae and 1-50 parts of radix glycyrrhizae. A preparation method of the anti-allergic compound polysaccharide composition includes the following steps: (1) crushing the raw materials into powder; (2) material feeding: adding water or a water-alcohol mixture by 5-50 times by weight of the powder into the powder; (3) extraction: performing extraction under -0.1-70 MPa at 0-25 DEG C, and performing centrifugal separation and collecting a centrifugate; (4) separation and concentration: removing impurities from the centrifugate through a micro-filtering membrane, and performing classification purification to the polysaccharide through an ultra-filtering membrane being 100-20000 Da in flux. The compound polysaccharide composition has the following beneficial effects: (1) the composition has definite anti-allergic functional components and is easy to control in quality; (2) the composition has a synergistic effect on a sensitizing target point with multiple links, is free of toxic and side effects and is high in safety; (3) the composition is free of contact with organic solvents, is free of residue of toxicity; and the preparation method is simple in process and is easy to carry out, and is suitable for being popularized industrially.

Description

technical field [0001] The invention relates to a compound polysaccharide composition, more specifically, an anti-allergic compound polysaccharide composition applicable to anti-allergic medicines and cosmetics for preventing skin allergies and its preparation method and application. Background technique [0002] Human allergy is a complicated process, which is closely related to the five aspects of the body's immunoglobulin IgE, nuclear factor betaprotein, interleukin-8, tumor necrosis factor-α and histamine. It is a relatively effective, direct and comprehensive way to prevent and treat allergies by working on the five key links. As an active ingredient widely distributed in plants, polysaccharides have unique advantages in the field of anti-allergic applications. [0003] For the anti-allergic mechanism of polysaccharides, traditional Chinese medicine believes that the corresponding effect is mainly achieved by regulating the immune function of the body. With the develo...

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Problems solved by technology

These methods inevitably lead to solvent residues

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