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A kind of traditional Chinese medicine composition and preparation thereof for treating cardiovascular and cerebrovascular diseases

A technology of pharmaceutical preparations and compositions, applied in the field of traditional Chinese medicine compositions for Xiaoshuantongluo and its preparations, which can solve problems such as inability to take care of oneself, relatives and social burdens

Active Publication Date: 2016-08-17
HARBIN KANGLONG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In my country, the proportion of deaths due to cardiovascular and cerebrovascular diseases to the total death population has risen from 12.07% in 1957 to 42.6% in 2001, and 2 million people died of cardiovascular and cerebrovascular diseases every year. Survived after being rescued, but most of them are left with disabilities and cannot take care of themselves, causing serious burdens to relatives and society

Method used

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  • A kind of traditional Chinese medicine composition and preparation thereof for treating cardiovascular and cerebrovascular diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] The preparation of embodiment 1 Xiaoshuan Tongluo Tablet

[0014] Grind Panax notoginseng and natural borneol into fine powder; decoct the other nine traditional Chinese medicines with water three times, add 10 times the amount of water for the first time, soak for more than 30 minutes, and decoct for 2 hours; add 8 times the amount for the second and third times respectively Water, decoct for 1 hour each, combine the decoctions, filter, and concentrate the filtrate under reduced pressure to obtain an extract (15.6g) with a relative density of 1.17-1.19 (80°C), add Sanqi fine powder, dry, and add 76.3g of auxiliary materials , dried, added borneol fine powder, mixed evenly, pressed into tablets, film-coated to obtain (tablet weight 380mg).

[0015] The dosage of each flavor of traditional Chinese medicine is 287g of Chuanxiong, 215g of Salvia, 431g of Astragalus, 144g of Alisma, 144g of Sanqi, 72g of Sophora japonica, 144g of Guizhi, 144g of Turmeric, 72g of Woody, 5.7g...

Embodiment 2

[0016] The impact of embodiment 2 borneol types on the pharmacological activity of Chinese medicine composition

[0017] 1) Preparation of traditional Chinese medicine composition

[0018] Grind notoginseng and borneol into fine powder; decoct the other nine traditional Chinese medicines with water three times, add 10 times the amount of water for the first time, soak for more than 30 minutes, and decoct for 2 hours; add 8 times the amount of water for the second and third times respectively , each decocted for 1 hour, combined the decoctions, filtered, the filtrate was concentrated under reduced pressure into an extract (15.6g) with a relative density of 1.17-1.19 (80°C), added Sanqi and borneol fine powder, and dried to obtain. The dosage of medicinal materials is the same as in Example 1, and two kinds of traditional Chinese medicine compositions are prepared by using artificial borneol and natural borneol respectively, which are natural borneol group and artificial borneol...

Embodiment 3

[0024] Embodiment 3 adjuvant composition is to the stability influence of Xiaoshuan Tongluo tablet

[0025] Different comparative examples were prepared according to the method of Example 1, stored at high temperature and high humidity (45° C., relative humidity 75%) for 6 months, and the content of main active ingredients in Xiaoshuan Tongluo Tablets were determined by HPLC. The medicinal material consumption and auxiliary material consumption of comparative example are all with embodiment 1, and the parts by weight of each comparative example auxiliary material are as follows:

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Abstract

The invention relates to a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases and a preparation thereof, belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for eliminating thrombus and dredging collaterals and a preparation thereof. The composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 200-300 parts of ligusticum wallichii, 200-300 parts of salvia miltiorrhiza, 300-500 parts of astragalus membranaceus, 100-200 parts of rhizoma alismatis, 100-200 parts of pseudo-ginseng, 10-100 parts of sophora japonica, 100-200 parts of cassia twig, 100-200 parts of radix curcumae, 10-100 parts of radix aucklandiae, 1-10 parts of natural borneol and 100-200 parts of hawthorn.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for eliminating blood clots and dredging collaterals and a preparation thereof. Background technique [0002] According to my country's epidemiological survey, the incidence and mortality of cardiovascular and cerebrovascular diseases have been on the rise in the past 50 years, whether in rural areas or cities. In the 1950s and 1960s, cardiovascular disease and cerebrovascular disease ranked fifth and sixth respectively among the causes of death in my country, and rose to second and third respectively after 1970. Cardiovascular and cerebrovascular diseases accounted for the first of all causes of death. In my country, the proportion of deaths due to cardiovascular and cerebrovascular diseases to the total death population has risen from 12.07% in 1957 to 42.6% in 2001, and 2 million people died of cardiovascular a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P9/00A61P9/10A61K31/045
Inventor 穆滨何林周浩天
Owner HARBIN KANGLONG PHARM CO LTD