Traditional Chinese medicine electuary for treatment and nursing of ICU myasthenia gravis and preparation method

Abstract

The invention discloses traditional Chinese medicine electuary for treatment and nursing of ICU myasthenia gravis and a preparation method and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine electuary is prepared from ficus beecheyana hook, Chinese dates, uncaria roots, mucuna sempervirens, triple shot range, milkvetch roots, ventilago leiocarpa benth, silverweed cinquefoil roots, wild black soybeans, lotus leaves, tuber fleeceflower stems, liquorice, akebiaquinata roots, pawpaws, cynachum uilfordii hemsl, radix paeoniae alba, glossy privet fruits, radix angelicae pubescentis, rattlesnake plantain, Sichuan cinnamon, cortex acanthopanacis, fructus amomi, gynostemma pentaphylla and antelope's horns. The medicine properties of the selected medicinal materials are adaptive and complementary, the medicine is applied pointing to symptoms according to pathogenesis, the effects of tonifying the liver and kidney, tonifying the spleen and raising yang, invigorating qi and blood, strengthening tendons and bones, relaxing tendons and activating collaterals and promoting qi to activate blood are achieved, the absorption effect is good, the curative effect is remarkable, no toxic or side effect or clinical adverse reaction is generated, and the traditional Chinese medicine electuary is high in cure rate for myasthenia gravis through clinical verification.

Description

Technical field

[0001] The invention relates to the field of traditional Chinese medicines, in particular to traditional Chinese medicine granules used for the treatment and nursing of ICU myasthenia gravis and a preparation method thereof. Background technique

[0002] Myasthenia gravis (MG) is an autoimmune disease caused by dysfunction of the nerve-muscle junction. The main clinical manifestations are partial or general skeletal muscle weakness and easy fatigue. The symptoms are aggravated after activities and relieved after rest. . The prevalence rate is 77-150 / 1 million, and the annual incidence rate is 4-11 / 1 million. The disease is more common in women than men and usually begins between the ages of 20 and 40, but can occur at any age. The most common symptoms are weakness of the eyelids (ptosis), weakness of the eye muscles, which can cause double vision, and muscles that tire especially after activities. In patients with myasthenia gravis, the eye muscles are aff...

Examples

Embodiment 1

[0052] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0053]

[0054] The processing steps of the pharmaceutical preparation method of the present invention are:

[0055] (1) Wash the milk pulp root, jujube, Uncaria root, Pteris ginseng, fern hemp, wild beans, lotus leaf, night cross vine, licorice, Geshanxiao, Sichuan cinnamon bark, Wujia bark, amomum, gynostemma , Mix evenly after drying, put into a container, add 6 to 8 times the amount of water in the container, heat and boil for 2 to 3 hours, take the infusion after cooling; add 4 to 6 times the amount to the remaining medicinal residues water, heated and boiled for 1 to 2 hours, and the infusion solution was taken after cooling; the infusion solution obtained by combining two times was heated, evaporated and concentrated into a thick paste with a relative density of 1.15 to 1.25, and set aside;

[0056] (2) Put Niu Ma Teng, Xuefeng Teng, Akebia Root, Duhuo...

Embodiment 2

[0065] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0066]

[0067] The process steps, usage and dosage of the medicine preparation method in this embodiment are the same as those in Example 1.

Embodiment 3

[0069] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0070]

[0071]

[0072] The process steps, usage and dosage of the medicine preparation method in this embodiment are the same as those in Example 1.

[0073] clinical information:

[0074] 1. Case selection

[0075] 80 cases of myasthenia gravis patients diagnosed in our hospital were selected for clinical observation. Patients with myasthenia gravis who had thymoma or enlarged thymus and needed surgery were not selected as cases. Patients were randomly divided into two groups. The treatment group consisted of 40 cases, including 13 males and 27 females, aged from 11 to 64 years, with an average age of 27.6 years. The shortest course was 1 month, and the longest course was 3 years, with an average of 0.8 years. The control group included 40 cases, including 14 males and 26 females, aged 12 to 63 years, with an average age of 26.5 years. The shortest co...

Technical field

[0001] The invention relates to the field of traditional Chinese medicines, in particular to traditional Chinese medicine granules used for the treatment and nursing of ICU myasthenia gravis and a preparation method thereof. Background technique

[0002] Myasthenia gravis (MG) is an autoimmune disease caused by dysfunction of the nerve-muscle junction. The main clinical manifestations are partial or general skeletal muscle weakness and easy fatigue. The symptoms are aggravated after activities and relieved after rest. . The prevalence rate is 77-150 / 1 million, and the annual incidence rate is 4-11 / 1 million. The disease is more common in women than men and usually begins between the ages of 20 and 40, but can occur at any age. The most common symptoms are weakness of the eyelids (ptosis), weakness of the eye muscles, which can cause double vision, and muscles that tire especially after activities. In patients with myasthenia gravis, the eye muscles are aff...

Examples

Embodiment 1

[0052] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0053]

[0054] The processing steps of the pharmaceutical preparation method of the present invention are:

[0055] (1) Wash the milk pulp root, jujube, Uncaria root, Pteris ginseng, fern hemp, wild beans, lotus leaf, night cross vine, licorice, Geshanxiao, Sichuan cinnamon bark, Wujia bark, amomum, gynostemma , Mix evenly after drying, put into a container, add 6 to 8 times the amount of water in the container, heat and boil for 2 to 3 hours, take the infusion after cooling; add 4 to 6 times the amount to the remaining medicinal residues water, heated and boiled for 1 to 2 hours, and the infusion solution was taken after cooling; the infusion solution obtained by combining two times was heated, evaporated and concentrated into a thick paste with a relative density of 1.15 to 1.25, and set aside;

[0056] (2) Put Niu Ma Teng, Xuefeng Teng, Akebia Root, Duhuo...

Embodiment 2

[0065] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0066]

[0067] The process steps, usage and dosage of the medicine preparation method in this embodiment are the same as those in Example 1.

Embodiment 3

[0069] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0070]

[0071]

[0072] The process steps, usage and dosage of the medicine preparation method in this embodiment are the same as those in Example 1.

[0073] clinical information:

[0074] 1. Case selection

[0075] 80 cases of myasthenia gravis patients diagnosed in our hospital were selected for clinical observation. Patients with myasthenia gravis who had thymoma or enlarged thymus and needed surgery were not selected as cases. Patients were randomly divided into two groups. The treatment group consisted of 40 cases, including 13 males and 27 females, aged from 11 to 64 years, with an average age of 27.6 years. The shortest course was 1 month, and the longest course was 3 years, with an average of 0.8 years. The control group included 40 cases, including 14 males and 26 females, aged 12 to 63 years, with an average age of 26.5 years. The shortest co...

Images