Method for extracting vitamin K2 from vitamin K2 embedding medium and method for detecting vitamin K2

A technology for vitamins and embedding agents, which is applied in the field of analytical chemistry and can solve the problems of difficult determination of vitamin K2 content, unstable vitamin K2, inability to determine vitamin K2 and the like
CN105301148AInactive Publication Date: 2016-02-03BY HEALTH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BY HEALTH CO LTD
Publication Date
2016-02-03
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to the field of analytical chemistry, in particular to a method for extracting vitamin K2 from a vitamin K2 embedding medium and a method for detecting the vitamin K2. According to the methods, the vitamin K2 embedding medium and acid are mixed, then subjected to ultraphonic processing, and then mixed with an organic solvent, the mixture is subjected to ultraphonic processing, and then the mixture is mixed with an organic solvent. The linearity, precision, repeatability, stability, blank, detection limit, quantitation limit and recovery experiments are carried out on the method for measuring the content of the vitamin K2, all the indexes meet the requirement of the GB / T27404-2008 laboratory quality control standard, it proves that the content measuring method is scientific and effective, and the quality control aim on the content of the vitamin K2 in the vitamin K2 compound preparation (embedding medium) can be achieved.
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Description

technical field

[0001] The invention relates to the field of analytical chemistry, in particular to a method for extracting vitamin K2 from a vitamin K2 embedding agent and a method for detecting vitamin K2. Background technique

[0002] Vitamin K2, also known as menaquinone, its structure is composed of a menaquinone mother ring and an isoprene side chain at the C-3 position of the mother ring, according to the number of isoprene units on the side chain According to the difference in number, vitamin K2 is divided into 14 kinds, represented by MK-n, and MK-7 contains 7 isoprene units on the side chain. Vitamin K2 has pharmacological activities such as promoting blood coagulation, preventing and treating osteoporosis, improving arteriosclerosis, preventing and treating liver cancer and leukemia.

[0003] Vitamin K2 is unstable when exposed to alkali and light, and is easy to decompose, but resistant to heat and acid. The stability of vitamin K2 in the compound preparation i...

Claims

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