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Phototoxicity exposure experimental animal fixing and protecting device

A technology for experimental animals and exposure experiments, applied in the field of fixed protection devices for phototoxic exposure experimental animals, which can solve problems such as operator injury, affecting the accuracy of test results, and pollution.

Inactive Publication Date: 2016-02-24
TIANJIN HOPE IND & TRADE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, in the fields of daily chemicals, new drug development, food and drug safety testing, skin pathology and other fields, the special needs of light allergy and disease-causing scientific research are increasingly paid attention to, especially some special light environments such as long-term work in ultraviolet radiation and strong light What kind of damage will be caused to the skin of personnel in the irradiated environment, as well as the protection method and effect research, etc. need to be proved by scientific experiments. At present, the common way to fix small animals in phototoxicity exposure experiments is to use ropes to fix the limbs of small animals. Fix it on a flat plate, expose an area on the back and directly irradiate it with a specific exposure light, cover the unirradiated part with adhesive tape, then measure it with a light intensity measuring instrument and observe the effect of the experiment with the naked eye. One foot, it is both troublesome and not firm to operate, the small animal often breaks free in the middle of the experiment, causing the irradiated part to move and the experiment fails. The damage caused by phototoxicity affects the accuracy of the test results; and the small animals have to excrete at any time during the experiment. Without the collection device, the experimental environment will be polluted and the operator will also be harmed; therefore, a phototoxic exposure experiment was developed. Immobilization and protection of experimental animals can be completed conveniently, quickly and safely, and small animal excrement can be collected at any time without causing environmental pollution. The immobilization and protection device for experimental animals with phototoxic exposure has become an urgent need at present.

Method used

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  • Phototoxicity exposure experimental animal fixing and protecting device

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Embodiment

[0019]When using, it is first necessary to determine whether the experimental animal 29 used in the phototoxic radiation exposure experiment is a mouse, rat, guinea pig or rabbit, and then select different sizes of phototoxic exposure experimental animal fixed protection devices, and collect the feces. The movable manure tank 8 of the device 9 is extracted, cleaned and inserted into the front manure tank frame 10 and the rear manure tank frame 7 and fixed to facilitate receiving feces; according to the relevant standards of the phototoxic radiation exposure experiment, the experimental animal 29 was removed before the experiment. The skin on both sides of the spine is depilated for backup. The skin of the test site must be intact, without damage or abnormality. Prepare 4 depilatory areas, each depilatory area is about 2cm×2cm; adjust the fixed protection of phototoxic exposure experimental animals according to the requirements of the experiment. For the height and flatness of t...

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Abstract

The invention provides a phototoxicity exposure experimental animal fixing and protecting device. The phototoxicity exposure experimental animal fixing and protecting device comprises a circular fixing frame which is arranged on a plane-shaped bottom plate and can fix experimental animals. An adjustable covering device and a side ejecting device are arranged on the circular fixing frame. A fixing shackle is arranged on the front side of the circular fixing frame and can clamp experimental animals. A top covering plate connected with the upper end of a front vertical plate at the front end of the bottom plate protects heads of experimental animals against phototoxic damage when conducting downward covering. A belly ejecting device is arranged at the bottom of the circular fixing frame and ejects back exposed epidermis of experimental animals so that the back exposed epidermis can not move when receiving phototoxicity exposure experiments. An excrement leakage opening located at excretory pores of experimental animals is located in the rear portion of the bottom plate. An excrement collector special for collecting excrement excreted by experimental animals is arranged below the excrement leakage opening. Four supporting leg frames are arranged at the four corners of the bottom plate and can adjust the height and the flatness. The phototoxicity exposure experimental animal fixing and protecting device has the advantages that the device which can conveniently, rapidly and safely complete experimental animal fixation and protection when phototoxicity exposure experiments are conducted is developed, and problems on this aspect are solved.

Description

technical field [0001] The invention relates to a fixed protection device for phototoxic exposure experimental animals. Background technique [0002] At present, in the fields of daily chemicals, new drug development, food and drug safety testing, skin pathology and other fields, the special needs of light allergy and disease-causing scientific research are increasingly paid attention to, especially some special light environments such as long-term work in ultraviolet radiation and strong light What kind of damage will be caused to the skin of personnel in the irradiated environment, as well as the protection method and effect research, etc. need to be proved by scientific experiments. At present, the common way to fix small animals in phototoxicity exposure experiments is to use ropes to fix the limbs of small animals. Fix it on a flat plate, expose an area on the back and directly irradiate it with a specific exposure light, cover the unirradiated part with adhesive tape, ...

Claims

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Application Information

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IPC IPC(8): A61D3/00
CPCA61D3/00A61D2003/003
Inventor 范维林张贵祥
Owner TIANJIN HOPE IND & TRADE
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