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Traditional Chinese medicine for treating tuberculosis by combination with anti-tuberculosis western medicine

A technology of pulmonary tuberculosis and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine combined with anti-waterlogging drugs to treat pulmonary tuberculosis, and achieves the effect of good therapeutic advantages.

Inactive Publication Date: 2016-05-04
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The two adjuvant treatment options have their own advantages and disadvantages, but through the analysis of PUBMED and Wanfang database, there are no reports on the systematic evaluation and comparative study of traditional Chinese medicine and immunomodulators, especially the study of pharmacoeconomics
Therefore, there are certain problems in the clinical application of immunomodulators or traditional Chinese medicines, including the timing of application, suitable population, length of treatment, frequency of administration, clinical efficacy, adverse reactions, etc.

Method used

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  • Traditional Chinese medicine for treating tuberculosis by combination with anti-tuberculosis western medicine
  • Traditional Chinese medicine for treating tuberculosis by combination with anti-tuberculosis western medicine
  • Traditional Chinese medicine for treating tuberculosis by combination with anti-tuberculosis western medicine

Examples

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preparation example Construction

[0034] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine, comprising:

[0035] The first step is to weigh each raw drug component according to the above-mentioned parts by weight, wash them separately, pulverize them into powder, mix them together, add 10 to 15 times the amount of water relative to the total weight of the mixture, and decoct 1 to 3 times. Filtrate for 1 to 3 hours each time to obtain the filtrate, collect the distillate obtained during each decoction, combine the filtrate and the distillate, concentrate until the relative density is 1.10 to 1.12 at 60°C, and obtain a clear Paste; add ethanol to make the volume alcohol content reach 50-80%, stir evenly, let it stand overnight, take the supernatant to recover ethanol under reduced pressure, and concentrate until the relative density is 1.07-1.09 at 60°C to obtain a secondary clear paste ;

[0036] In the second step, add auxiliary materials to the secon...

Embodiment 1

[0071] Embodiment 1 oral liquid 1

[0072] Take 40g of Codonopsis pilosula, 35g of ginseng, 30g of astragalus, 20g of fried Atractylodes macrocephala, 10g of Pinellia chinensis, 20g of poria cocos, 10g of cassia twig, 20g of northern sand ginseng, 30g of Ophiopogon japonicus, 15g of lily, 10g of coltsfoot flower, 30g of schisandra, and 15g of silver bupleurum. , Agrimony 15g, Arborvitae leaves 15g, Bletilla striata 20g, Bletilla 25g, Panax notoginseng 30g, lotus root 15g, stamens 15g, ephedra root 15g, floating wheat 20g, donkey-hide gelatin 20g, Zhiguijia 15g, rehmannia 20g, Wash 30g sheepskin, 20g Ziheche, 25g Ligustrum lucidum, 20g Bupleurum bupleuri and 15g Corydalis Corydalis, wash them separately, grind them into powder, mix them together, add 12 times the amount of water relative to the total weight of the mixture, decoct 3 times, Filtrate for 2 hours each time to obtain the filtrate, and collect the distillate obtained during each decoction at the same time, combine th...

Embodiment 2

[0073] Embodiment 2 oral liquid 2

[0074] Take 40g of Codonopsis pilosula, 35g of ginseng, 25g of astragalus, 15g of fried Atractylodes macrocephala, 10g of Pinellia chinensis, 15g of poria cocos, 10g of cassia twig, 20g of northern sand ginseng, 25g of Ophiopogon japonicus, 15g of lily, 10g of coltsfoot flower, 25g of schisandra, and 15g of silver bupleurum. , Agrimony 15g, Arborvitae leaves 10g, Bletilla striata 20g, Baishui 25g, Panax notoginseng 25g, lotus node 10g, stamen 10g, ephedra root 15g, floating wheat 15g, donkey-hide gelatin 20g, 15g made turtle shell, 20g rehmannia glutinosa, 30g sheepskin, 15g Ziheche, 25g Ligustrum lucidum, 20g Bupleurum and 15g Corydalis, wash separately, grind into powder, mix together, add 12 times the amount of water relative to the total weight of the mixture, decoct 3 times, Filtrate for 2 hours each time to obtain the filtrate, and collect the distillate obtained during each decoction at the same time, combine the filtrate and the dist...

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Abstract

The invention provides a traditional Chinese medicine for treating tuberculosis by combination with an anti-tuberculosis western medicine. The traditional Chinese medicine comprises the following active pharmaceutical ingredients: codonopsis pilosula, ginseng, astragalus membranaceus, fried atractylodes macrocephala, rhizoma pinelliae preparata, poria cocos, cassia twig, radix glehniae, ophiopogon root, lily, flos farfarae, schisandra chinensis, radices stellariae dichotomae, agrimonia pilosa, cacumen biotae, bletilla striata, radix ampelopsis, panax notoginseng, lotus rhizome node, ophicalcite, radix ephedrae, light wheat, donkey-hide gelatin, prepared turtle shell, radix rehmanniae recen, epimedium, human placenta, fructus ligustri lucidi, radix bupleuri and rhizoma corydalis. According to a clinical comparison for cost-effect analysis between the traditional Chinese medicine and an immunomodulator, the traditional Chinese medicine has the very good treatment advantage, thereby being worth of clinical promotion.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine used in combination with anti-waterlogging medicine for treating pulmonary tuberculosis. Background technique [0002] 1.1 The task of tuberculosis prevention and control is still arduous [0003] Tuberculosis (wherein pulmonary tuberculosis accounts for about 80% to 90%) is an important public health problem and a respiratory infectious disease that seriously endangers public health, and is listed as one of the major infectious diseases in my country. According to the World Health Organization statistics report, there are 2 billion people infected with Mycobacterium tuberculosis (MTB) in the world, including 20 million cases of active pulmonary tuberculosis patients. About 550 million people in my country are infected with MTB, and it is estimated that there are about 4.5 million cases of active pulmonary tuberculosis. my cou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P31/06A61P11/00A61K33/10A61K35/36A61K35/50A61K35/586
CPCA61K36/344A61K9/0053A61K9/08A61K33/10A61K35/36A61K35/50A61K35/586A61K36/076A61K36/14A61K36/17A61K36/23A61K36/233A61K36/258A61K36/28A61K36/284A61K36/296A61K36/36A61K36/481A61K36/54A61K36/57A61K36/62A61K36/638A61K36/66A61K36/73A61K36/79A61K36/804A61K36/87A61K36/8888A61K36/8967A61K36/8968A61K36/898A61K36/899A61K47/26A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 刘雪
Owner QINGDAO MUNICIPAL HOSPITAL
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