Medicine for treating children stomatitis and preparation method of medicine

A technology of stomatitis and medicine, which is applied in the field of medicine and its preparation for the treatment of children's stomatitis, can solve the problems of treating the symptoms but not the root cause, large side effects, and the defects of patient dependence, and achieves definite curative effect, quick onset of effect, long treatment course short effect

Inactive Publication Date: 2016-06-01
济南思拓新源医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, the oral medicines for the treatment of stomatitis in children have large side effects, treat the symptoms but not the root cause, and the long-term use of patients has the defect of dependence

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0062] When the dosage form of the medicine is a granule, its preparation method may comprise the following steps:

[0063] The first step is to mix the various raw materials of the drug according to the stated ratio, add ethanol with an alcohol concentration of 4 to 8 times that of the mixture, and heat it to boiling and reflux for 3 to 5 hours, filter, and use osmotic Slowly percolate at a speed of 1-2ml per minute by roller method, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C, and spray dry , the air inlet temperature of the spray dryer is 160-175°C, the outlet air temperature is 80-85°C, and then crushed into powder to make dry paste powder;

[0064] In the second step, 0.2-0.4 times of sucrose powder and 0.1-0.2 times of dextrin are added to the obtained dry paste powder to form granules, and dried at 40-50° C. to obtain granules.

[0065] When the dosage for...

Embodiment 1

[0077] Embodiment 1 Granules

[0078] The preparation process of the granule of the present invention is as follows: get 15 parts by weight of barley dendrobium, 28 parts by weight of pistil tea, 16 parts by weight of Chinese spinach, 24 parts by weight of lobes, 15 parts by weight of basil, 32 parts by weight of kudzu juice, 16 parts by weight of shaozi, 20 parts by weight of scorpion, 34 parts by weight of dipixiao, 21 parts by weight of bamboo leaves, 13 parts by weight of snake lotus, 9 parts by weight of ginseng, 27 parts by weight of purple pearl, 14 parts by weight of Artemisia annua, 17 parts by weight of kudzu root, 23 parts by weight of valerian, 10 parts by weight of daigo and 27 parts by weight of jinbuhuan;

[0079]The first step is to mix the raw materials and medicinal materials of the medicine according to the stated ratio, add ethanol with an alcohol concentration of 5 times that of the mixture and be 90% ethanol, heat to boiling and reflux for 4 hours, filter...

Embodiment 2

[0081] Embodiment 2 spray

[0082] The preparation process of the spray of the present invention is as follows: get 18 parts by weight of barley dendrobium, 30 parts by weight of pistil tea, 14 parts by weight of Chinese spinach, 33 parts by weight of lobster, 21 parts by weight of basil, 32 parts by weight of kudzu juice, 11 parts by weight of shaozi, 21 parts by weight of scorpion, 35 parts by weight of dipixiao, 19 parts by weight of bamboo leaves, 13 parts by weight of snake lotus, 16 parts by weight of ginseng, 25 parts by weight of purple pearl, 14 parts by weight of Artemisia annua, 11 parts by weight of kudzu root, 24 parts by weight of valerian, 7 parts by weight of daigo and 28 parts by weight of jinbuhuan;

[0083] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixed powder composed of micron-sized particles with a volume average particle size of 7 μm and nano-sized particles with a volu...

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Abstract

The invention discloses a medicine for treating children stomatitis and a preparation method of the medicine. The medicine comprises the following raw herbal materials: bulbophyllum inconspicuum, camellia fraterna hance, rorippa montana, pterocephalus bretschneideri, ocimum basilicum, vitis flexuosa vine juice, nephelium chryseum, litsea glutinosa, pararuellia delavayana, lophatherum gracile, coriaceous knotweed rhizome, polygonum bistorta, callicarpa pedunculata, artemisia argyi, pouzolzia zeylanica, valeriana officinalis, clarified butter and stephania sinica diels. The medicine has the benefits that the efficacies of nourishing yin and reducing swelling, clearing heat and removing toxicity, diminishing inflammation and stopping pain, and removing stasis and stopping blood are achieved, and the advantages of quick effect, high effective rate, precise curative effect, short treatment course, zero toxic and side effect, low cost and the like are achieved.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating stomatitis in children and a preparation method thereof. Background technique [0002] Stomatitis refers to the inflammation of the oral mucosa caused by various infections. If the lesions are limited to local areas such as the tongue, gums, and corners of the mouth, it can also be called glossitis, gingivitis, or angular cheilitis. The disease is more common in infants and young children. It can occur alone, or it can be secondary to systemic diseases such as acute infection, diarrhea, malnutrition, prolonged illness and weakness, and vitamin B and C deficiency. Infections are often caused by viruses, fungi, and bacteria. Factors such as not paying attention to tableware and oral hygiene or various diseases that lead to a decrease in the body's resistance can lead to the occurrence of stomatitis. [0003] Several common stomatitis a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P1/02A61P31/04A61P31/22A61K35/20
CPCA61K36/898A61K9/006A61K9/1652A61K35/20A61K36/185A61K36/19A61K36/27A61K36/28A61K36/31A61K36/48A61K36/53A61K36/54A61K36/59A61K36/704A61K36/77A61K36/82A61K36/85A61K36/87A61K36/899A61K47/26A61K2236/331A61K2236/333A61K2236/51A61K2236/53A61K2300/00
Inventor 王磊
Owner 济南思拓新源医药科技有限公司
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