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Application of paliurus ramosissimus (Lour.) poir or extract thereof in preparing medicine for treating infectious ulcer

A kind of extract and technology of Majiazi, which is applied in the field of medicine, can solve the problems of aggravated infection, unclear relationship between growth factors, prolonged course of disease, etc.

Active Publication Date: 2016-07-27
四川梓橦宫药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine mainly adopts debridement, antibacterial, repairing and other methods of treatment. However, there are still many unresolved problems, such as the application of antibiotics during the infection period. Due to the emergence of a large number of drug-resistant strains, antibiotics are ineffective, and its toxic side effects, such as allergic reactions Etc. make the infection aggravate and prolong the course of the disease
Clinical studies have shown that many experimentally sensitive drugs are not effective after clinical use, and surgical treatment methods, such as conventional debridement and enzymatic debridement, have major problems. Until the use of growth factors, the mechanism of tissue repair has not yet been fully understood, and the relationship between each growth factor is not very clear, and its use is also greatly limited.

Method used

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  • Application of paliurus ramosissimus (Lour.) poir or extract thereof in preparing medicine for treating infectious ulcer
  • Application of paliurus ramosissimus (Lour.) poir or extract thereof in preparing medicine for treating infectious ulcer
  • Application of paliurus ramosissimus (Lour.) poir or extract thereof in preparing medicine for treating infectious ulcer

Examples

Experimental program
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Effect test

preparation example Construction

[0066] 1. Preparation of whole plant water extract

[0067] Take 5 kg of the whole plant of S. japonicus, grind it, add 8 times the amount of water to decoct and extract it for 3 times, collect the extract, concentrate under reduced pressure and dry to obtain the water extract of S. japonicus.

[0068] 2. Preparation of whole plant ethanol extract

[0069] Take 5 kg of the whole plant of Fructus Sinica, crush it, add 8 times the amount of 95% ethanol to immerse and extract several times, collect the extract, recover the ethanol under reduced pressure until it has no alcohol smell, and dry it to obtain the ethanol extract of Fructus Sinensis.

[0070] 3. Preparation of stem and leaf ethanol, petroleum ether and ethyl acetate extracts

[0071] Take 5 kg of stems and leaves of S. japonicus and crush them, add 10 times the amount of 95% ethanol to reflux for extraction several times, collect the extract, recover the ethanol under reduced pressure at 60° C. until there is no alcoh...

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Abstract

The invention belongs to the field of medicine, and relates to a novel application of paliurus ramosissimus (Lour.) poir or an extract thereof, in particular to an application of the paliurus ramosissimus (Lour.) poir or the extract thereof in preparing a medicine for treating infectious ulcer. The paliurus ramosissimus (Lour.) poir and the extract thereof, when externally applied, can effectively promote healing of the infectious ulcer, with both time of taking effect and therapeutic effect better than that of clinically common control drugs, showing that the paliurus ramosissimus (Lour.) poir and the extract thereof are more excellent than existing common drugs in curative effect on treating the infectious ulcer.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a new application of the vetch seed or its extract, in particular to the use of the safflower seed or its extract in the preparation of medicine for treating infectious ulcers. Background technique [0002] Paliurus ramosissimus (Lour.) Poir is a deciduous shrub, which is a common medicinal plant. It is reported that the branches, leaves, roots, flowers and fruits are all medicinal. Nature and flavor are bitter, flat, non-toxic. Can remove cold and activate blood circulation, release antipyretic, detumescence, control traumatic injury and trusted subordinate's pain. However, it has not been seen that S. chinensis and its extracts can be used to treat infected ulcers. [0003] Infected ulcers are manifested as bacterial skin and mucous membrane ulcerative injuries. During the pathogenesis, there are pathological changes such as wound exudation, infection, and erosion, as well as skin and m...

Claims

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Application Information

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IPC IPC(8): A61K36/72A61P17/02A61P31/04
CPCA61K36/72
Inventor 徐超群李东晓张毅阮佳谭镭詹雁
Owner 四川梓橦宫药业股份有限公司
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