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Xiaoerjiebiao granule with improved taste and preparation method thereof

A technology for children and granules, which is applied in the direction of medical preparations with non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, etc. It can solve the problems of bitter taste and limited application value of traditional Chinese medicine components

Active Publication Date: 2018-12-25
SICHUAN GOODDOCTOR PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the bitter taste of the traditional Chinese medicine components of this product, the application value of this variety is greatly limited due to the poor compliance of children taking medicine. very necessary and urgent

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1, the prescription research of mouthfeel improvement

[0020] The excipients used in this experiment were all purchased from reagent companies and met the standards for medicinal use, and the medicinal materials used were purchased from medicinal materials companies and met the standards of the Pharmacopoeia.

[0021] 1. Preparation of Xiaoerjiebiao Granule Thick Ointment

[0022] Prescription for Xiaoer Jiebiao Granules: 300g honeysuckle, 250g forsythia, 250g fried burdock, 300g dandelion, 300g skullcap, 150g windproof, 150g perilla, 100g nepeta panicle, 150g kudzu root, 1g artificial bezoar.

[0023] The above ten flavors, forsythia, perilla leaves, nepeta ears extract volatile oil (for spare), distilled water solution is collected separately; honeysuckle, fried burdock seeds, dandelion, scutellaria baicalensis, windproof, kudzu root, add water and decoct twice, the first time 2.5 hours, the second 1.5 hours, filter, the filtrate is combined with the abov...

Embodiment 2

[0046] Embodiment 2 clinical research

[0047] This investigation is realized in this way: by investigating the preference of children aged 2-14 for the two new formulas and the original formula, the children's favorite taste is selected, and then the comparison of the curative effects of the new formula and the original formula on children with colds is confirmed to confirm the new formula. The formula not only has a better taste, but also does not reduce the curative effect.

[0048] The following survey is intended to further illustrate the benefits of the present invention:

[0049] Investigation example one:

[0050] 1. Survey method

[0051] A total of 120 children aged 2-14 were randomly selected. They were divided into two groups according to their ages, among which 2-5 years old were group 1 (64 people), and 6-14 years old were group 2 (56 people). Take three kinds of Xiaoerjiebiao granules, which are the sweet and sour taste in Example 1, which are seasoned with ...

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PUM

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Abstract

The invention relates to exterior syndrome relieving granules for children with taste improved and a preparing method thereof. The granules are prepared from honeysuckle flower, fructus forsythia, fried fructus arctii, dandelion, radix scutellariae, radix sileris, folia perillae acutae, schizonepeta spike, radix pueraiae and calculus bovis factitious. The granules have a remarkable effect. However, existing exterior syndrome relieving granules for children are hardly accepted by clinical patients due to the bad taste. The formula of the exterior syndrome relieving granules for children with taste improved is improved by adding a sour agent, a sweetening agent, chocolate essence or other essence, so that two novel tastes are realized and a more suitable taste is screened out. The screened novel formula enables a better taste and makes children compliance higher on the premise that the original treatment effect is guaranteed.

Description

field of invention [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a process and method for improving the mouthfeel of Xiaoerjiebiao granules. technical background [0002] At present, there are about 220 million children in China. According to statistics, Chinese children catch an average of 3 colds per person per year, and the number of children with colds per year reaches more than 660 million. It can be seen that the children's cold medicine market is huge. With the opening of the second child in 2016, the number of children will reach a new high in the next few years, and the baby medicine market, especially the cold medicine market, will expand unprecedentedly. Therefore, the development and upgrading of children's cold medicines owned by the Group is in line with the general trend of the market. [0003] Xiaoer Jiebiao Granules are made of ten kinds of traditional Chinese medicines including honeysuckle, forsyt...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/26A61K47/12A61K47/46A61K36/634A61K9/16A61P11/00A61K35/413
CPCA61K9/1623A61K9/1664A61K35/413A61K36/238A61K36/28A61K36/288A61K36/355A61K36/488A61K36/535A61K36/538A61K36/539A61K36/634A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 耿福能沈咏梅吴宇吴桃清
Owner SICHUAN GOODDOCTOR PHARMA GRP