Optical three-dimensional imaging method based on voxel and adaptive optical transmission model

Abstract

The invention discloses an optical three-dimensional imaging method based on a voxel and an adaptive optical transmission model. With the method, a problem that an optical three-dimensional imaging reconstruction result can not be obtained until tedious organ segmentation and grid discretization are carried out in the prior art can be solved. According to the invention, a voxel physical model and an adaptive optical transmission mathematic model are combined organically; and a complete sparse regularization objective function is constructed and solved to realize optical three-dimensional imaging of a targeting object in vivo. The method comprises steps of data acquisition and pretreatment, voxel-based physical model construction, adaptive optical transmission mathematic model construction, system equation establishment based on enriched function fusion, objective function establishment based on a sparse regularization strategy and a prior feasible region, and objective function and display result solution. Therefore, the provided method has characteristics of high efficiency and easy usage; and an inaccurate three-dimensional imaging result due to an error caused by uncontrollable factors in organ segmentation and grid discretization can be avoided. The method can be applied to the in-vivo optical three-dimensional imaging field.

Description

technical field [0001] The invention belongs to the technical field of optical molecular imaging, in particular to an optical three-dimensional imaging method based on a voxel and an adaptive light transmission model. Background technique [0002] Optical 3D imaging is an emerging optical imaging technology. It reconstructs living organisms based on accurate light transmission models in biological tissues by fusing multi-angle optical signals measured on the surface of organisms, anatomical structures of organisms, and tissue optical parameter information. Position and intensity distribution information of targeted objects within the body. Among them, the accurate description of the light transmission process in biological tissue and the accurate and fast reconstruction of the target are the basis for the realization of the optical three-dimensional imaging method. Beijing University of Technology proposed a method in its patent application document "Multispectral autofluor...

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Problems solved by technology

[0004] The purpose of the present invention is to provide an optical three-dimensional imaging method based on voxel and adaptive light transmission model, aiming to solve the problem in the prior art that cumbersome organ segmentation and grid discretization are required to obtain optical three-dimensional imaging reconstruction results

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