Phenyl Linked Quinolinyl Modulators Of Ror-Gamma-T
A phenyl and methyl technology, applied in anti-inflammatory agents, non-central analgesics, medical preparations containing active ingredients, etc., can solve the problems of EAE sensitivity reduction and Th17 cell population reduction
Inactive Publication Date: 2016-08-03
JANSSEN PHARMA NV
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AI-Extracted Technical Summary
Problems solved by technology
The present invention comprises compounds of Formula I. Formula I wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR[gamma]t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
Organic active ingredientsNervous disorder +9
- Experimental program(97)
- Effect test(1)
Description & Claims & Application Information
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