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Pharmaceutical preparation for metastatic bone pain of thyroid cancer

A technology for thyroid cancer and pharmaceutical preparations, which can be used in drug combinations, non-central analgesics, medical raw materials derived from arthropods, etc. Karnofsky score value, the effect of improving quality of life

Inactive Publication Date: 2016-08-10
QINGDAO CHENDA BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Judging from the current literature, there are very few studies of traditional Chinese medicine on this disease, and there is no specific drug for the pain of bone metastases from thyroid cancer. Therefore, further research is necessary to enrich the comprehensive treatment of thyroid cancer.

Method used

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  • Pharmaceutical preparation for metastatic bone pain of thyroid cancer
  • Pharmaceutical preparation for metastatic bone pain of thyroid cancer
  • Pharmaceutical preparation for metastatic bone pain of thyroid cancer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment 1 capsule

[0042] Prescription: 20 servings of egg balm, 12 servings of edelweiss, 10 servings of touguxiang, 10 servings of eucommia, 15 servings of rehmannia glutinosa, 8 servings of mulberry, 8 servings of jellyfish, 12 servings of cicada, 6 servings of chrysalis , 10 parts of Bamboo Ginseng, 12 parts of Heart-protecting Grass, and 15 parts of Black Pitt Root.

[0043] Preparation:

[0044] (1) Get coniferous edelweiss, Touguxiang, scorpion celestial grass, and cicada by prescription to pulverize and mix, add 5 times the concentration of parts by weight and be 40% ethanol reflux extraction 2 times, the time of each heating reflux is After 1.0 to 1.5 hours, collect the filter residue after ethanol extraction of Edelweiss coniferae, Touguxiang, Lixeniaceae, and Scutellaria, combine the extracts, filter, and concentrate under reduced pressure to form a thick paste;

[0045] (2) According to the prescription, weigh Danbulao, Eucommia, Rehmannia glutinosa, S...

Embodiment 2

[0047] Embodiment 2 capsules

[0048] Prescription: 25 parts of egg bald, 15 parts of coniferous edelweiss, 10 parts of touguxiang, 12 parts of Eucommia, 18 parts of Rehmannia glutinosa, 8 parts of mulberry, 10 parts of jellyfish, 15 parts of cicada, 8 parts of chrysalis , 8 parts of Bamboo Ginseng, 12 parts of Heart-protecting Grass, and 15 parts of Black Pitt Root.

[0049] Preparation:

[0050] (1) get coniferous edelweiss, touguxiang, Xixiancao, Shichancao pulverizing, mixing by prescription, add the concentration of 6 times of weight parts and be 40% ethanol reflux extraction 2 times, the time of heating reflux at every turn is After 1.5 to 2 hours, collect the ethanol-extracted filter residues of Edelweiss coniferae, Touguxiang, Lixeniaceae, and Scutellaria, combine the extracts, filter, and concentrate under reduced pressure to form a thick paste;

[0051] (2) According to the prescription, weigh Danbulao, Eucommia, Rehmannia glutinosa, Sangjisi, Weetworm, Bamboo Gins...

Embodiment 3

[0053] Embodiment 3 capsules

[0054] Prescription: 22 parts of egg bald, 12 parts of coniferous edelweiss, 12 parts of touguxiang, 10 parts of Eucommia, 15 parts of rehmannia glutinosa, 9 parts of mulberry, 6 parts of jellyfish, 10 parts of chrysanthemum, and 6 parts of chrysalis , 8 parts of bamboo ginseng, 10 parts of heart-protecting grass, and 13 parts of black root.

[0055] Preparation method: (1) According to the prescription, take edelweiss coniferouse, touguxiang, Xixiancao and Shichancao, pulverize and mix, add 4 times by weight of ethanol with a concentration of 40% to reflux for extraction twice, and heat to reflux each time The time is 1.0 to 1.5 hours, collect the filter residue after ethanol extraction of Edelweiss coniferae, Touguxiang, Sixiancao, and Shichancao, combine the extracts, filter, and concentrate under reduced pressure to form a thick paste;

[0056] (2) According to the prescription, weigh Danbulao, Eucommia, Rehmannia glutinosa, Sangjisi, Weetwo...

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Abstract

The invention belongs to the field of medicines and particularly relates to a pharmaceutical preparation for metastatic bone pain of thyroid cancer and a preparation method of the pharmaceutical preparation. The pharmaceutical preparation is prepared from Cantonese Speranskia, Herba Leontopodii Subulati, Herba Speranskiae Tuberculatae, Cortex Eucommiae, Radix Rehmanniae Preparata, Herba Taxilli, Herba Siegesbeckiae, Dindygulen Peperomia Herb, Eupolyphaga seu Steleophaga, Rhizoma Panacis Japonici, Herba Cyperi Micheliani and Radix Polyalthiae Nemoralis. The pharmaceutical preparation has efficacies of blood circulation promoting, stasis removing, pain relieving, heat clearing, detoxifying, kidney tonifying and bone strengthening and is capable of effectively regulating functional balance of body Yin and Yang, Qi, blood and internal organs, relieving pains, resisting cancers, well improving immune functions of patients, improving disease resistance, reducing toxic and side effects of radiotherapy and chemotherapy and evidently improving life quality of the patients.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a pharmaceutical preparation for bone metastasis pain of thyroid cancer and a preparation method thereof. Background technique [0002] Thyroid cancer is a relatively common malignant tumor in the head and neck, accounting for 1% to 2% of systemic malignant tumors. It is more common in women and can be seen in any age group. At present, the incidence of thyroid cancer shows a significant upward trend year by year. Differentiated thyroid cancer is the most common pathological type of thyroid cancer, accounting for up to 90%. Differentiated thyroid cancer (DTC) usually develops slowly and has a low degree of malignancy. Therefore, when thyroid cancer is diagnosed clinically, most patients have metastasized to varying degrees, and most patients with thyroid cancer seek medical treatment for bone pain. [0003] Since DTC cells are 131 I has a better absorpti...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61P35/04A61P29/00A61K35/64
CPCA61K36/185A61K36/258A61K36/28A61K36/45A61K36/46A61K36/47A61K36/67A61K36/804A61K36/8905A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K35/63A61K2300/00
Inventor 陈令浩
Owner QINGDAO CHENDA BIOLOGICAL SCI & TECH
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