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A traditional Chinese medicine preparation for treating heart failure with normal ejection fraction

A technology for normal ejection fraction and heart failure, applied to medical preparations containing active ingredients, pharmaceutical formulas, drug combinations, etc., to achieve no obvious side effects, significant curative effect, and improve clinical curative effect

Active Publication Date: 2019-10-11
毛静远 +5
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to provide a traditional Chinese medicine preparation for the treatment of heart failure with normal ejection fraction, which makes up for the inadequacy of Western medicine alone in the treatment of heart failure with normal ejection fraction.

Method used

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  • A traditional Chinese medicine preparation for treating heart failure with normal ejection fraction
  • A traditional Chinese medicine preparation for treating heart failure with normal ejection fraction

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preparation example Construction

[0034] 1. The preparation method of water decoction comprises the following steps: after the crude drug is weighed by the above-mentioned portion, the turtle shell is soaked separately, and the rest of the medicine is packed into a disposable non-woven medicine bag, and the 3 ~ 5 cm of water, soak for 20-40 minutes; first fry the turtle shell in a decoction vessel (such as a casserole) for 30 minutes, then add other ingredients, bring to a boil over high heat, and then turn to low heat and cook for 30-40 minutes. After decocting, filter out the medicinal liquid to obtain 20,000 ml; in the second decoction, add an appropriate amount of water (preferably without the medicinal residue), boil on high heat, then turn to low heat and fry for about 20 minutes, filter the medicinal liquid, Get 10,000 milliliters of medicinal liquid; two medicinal liquids are mixed to obtain 30,000 milliliters of medicinal liquid. Each 150ml vacuum compression package is 1 bag.

[0035] Dosage: 2 time...

example 1

[0106] Case 1 Zhou, female, 80 years old, was hospitalized in the Cardiovascular Department of the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine in 2013 mainly due to "chest tightness, shortness of breath, and fatigue". Two stents were implanted in the crown, and Holter showed paroxysmal atrial fibrillation in 24 hours. The doctor suggested radiofrequency ablation or pacemaker implantation, but the patient refused, and was discharged after a slight improvement. After being discharged from the hospital, the patient's symptoms recurred, and the patient felt anxious and depressed, so he came to our hospital to seek Chinese medicine treatment. The first BNP check was 653pg / ml, and the cardiac color Doppler ultrasound showed that the interventricular septum / posterior wall thickness was 1.2. Western medicine diagnosis is "heart failure, cardiac function class III (NYHA), coronary atherosclerotic heart disease, coronary three-vessel disease, stent im...

example 2

[0107] Case 2 Gao, female, 75 years old, was hospitalized in the Cardiovascular Department of our hospital (The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine) 2 years ago. The western medicine diagnosis was "coronary heart disease, unstable angina, arrhythmia, Tremor, heart failure, cardiac function grade III (NYHA classification), hypertension grade 3", improved after treatment and was discharged. Symptoms recurred during the period, so I went to the outpatient clinic of our hospital for the treatment of integrated traditional Chinese and Western medicine. The first BNP test was 486pg / ml; the electrocardiogram showed atrial fibrillation; the result of cardiac color Doppler ultrasound was LVEF57%, interventricular septal / posterior wall thickness was 1.3, E / e' for 15.98. The traditional Chinese medical science is diagnosed as heart failure disease, and card belongs to syndrome of yin deficiency and blood stasis, phlegm-heat, then oral Chinese m...

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating heart failure with preserved ejection fraction. The traditional Chinese medicine preparation is prepared from the following ten traditional Chinese medicines according to a certain proportion: radix ophiopogonis, fructus corni, rhizoma polygonati, rhizoma coptidis, snakegourd peel, earthworm, turtle shell, radix salviae miltiorrhizae, rhizoma pinelliae, fructus aurantii and the like. The traditional Chinese medicine preparation is mainly used for treating the heart failure with preserved ejection fraction, or heart failure and other diseases having clinical syndromes of yin deficiency with blood stasis with or without phlegm and fluid retention, and has the effects of nourishing yin, benefiting qi, activating blood, expelling phlegm and promoting urination. The traditional Chinese medicine preparation is precise and appropriate in medicine use, rigorous in compatibility of medicines and remarkable in curative effect; compared with simple western medicine intervention, the traditional Chinese medicine preparation has the advantages of further improving the clinical symptoms and psychological state of a patient who has the heart failure with preserved ejection fraction or the heart failure having clinical syndromes of yin deficiency with blood stasis with or without phlegm and fluid retention, improving quality of life, increasing exercise tolerance, reducing rehospitalization rate, and the like; furthermore, the traditional Chinese medicine preparation is safe to take and free from obvious toxic or side effects, and can be popularized and applied clinically.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a traditional Chinese medicine preparation clinically used for treating heart failure with normal ejection fraction or heart failure whose clinical syndrome is manifested as yin deficiency and blood stasis with or without phlegm retention. Background technique [0002] Heart failure with normal ejection fraction was also called diastolic heart failure in the past. Different from the previous understanding, the morbidity and mortality of heart failure with normal ejection fraction are relatively high, showing a rising trend year by year, which has caused a heavy burden on human health. , the domestic literature reports that the incidence rate is 34.1%, and the foreign literature reports 56%. At the same time, heart failure with normal ejection fraction is mostly the elderly, and the prevention and treatment situation is not optimistic. Age, diabetes, hypertensi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8969A61P9/04A61K35/586A61K35/62
Inventor 毛静远赵志强王贤良毕颖斐侯雅竹王帅
Owner 毛静远
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