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Application of epigallocatechin gallate in preparing drug for preventing or treating bladder tumor

A technology of epigallocatechin and gallate, applied in the field of tumor treatment

Inactive Publication Date: 2016-12-14
THE SECOND PEOPLES HOSPITAL OF SHENZHEN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The source of tea polyphenol EGCG is natural and has no toxic side effects. It has a variety of health effects and is a potential natural medicine. However, its research on bladder cancer is rarely reported, although it has been reported that EGCG inhibits bladder cancer cells NBT-2, T24 The proliferation and migration of EGCG[5], but the molecular mechanism research and animal model verification of EGCG on bladder cancer SW780 have not been reported

Method used

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  • Application of epigallocatechin gallate in preparing drug for preventing or treating bladder tumor
  • Application of epigallocatechin gallate in preparing drug for preventing or treating bladder tumor
  • Application of epigallocatechin gallate in preparing drug for preventing or treating bladder tumor

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Embodiment Construction

[0021] The invention proves that the epigallocatechin gallate has a certain curative effect on bladder tumors, so it can be used as an active ingredient to prepare a medicine for preventing or treating bladder tumors.

[0022] In the present invention, epigallocatechin gallate can be used alone as a drug. Also can form pharmaceutical composition with other components, and other components comprise: pharmaceutically acceptable matrix, carrier, additive (such as excipient, binding agent, disintegrant, lubricant, solvent, sweetener, coloring agent, Flavoring agents, odor masking agents, surfactants, moisturizing agents, preservatives, pH regulators and thickeners), etc.

[0023] In the present invention, a pharmaceutically acceptable carrier refers to a non-toxic carrier, adjuvant or vehicle that will not destroy the pharmacological activity of the compound formulated with it. Pharmaceutically acceptable carriers, adjuvants or vehicles that can be used in the compositions of the...

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Abstract

The invention discloses an application of epigallocatechin gallate in preparing a drug for preventing or treating the bladder tumor. The invention proves that epigallocatechin gallate has a certain curative effect on the bladder tumor, and therefore the epigallocatechin gallate can be taken as a drug active ingredient for preparing the drug for preventing or treating bladder tumor.

Description

technical field [0001] The invention relates to the technical field of tumor treatment, in particular to the use of epigallocatechin gallate in the preparation of medicines for preventing or treating bladder tumors. Background technique [0002] Green tea is a common drink in China. It is naturally healthy and has a wide range of health benefits. Epigallocatechin gallate (EGCG) is the tea polyphenol with the highest content in green tea, and it is also one of the most important active ingredients in green tea. Studies have proved that tea polyphenol EGCG plays a role in preventing cardiovascular disease, anti-obesity, and anti-oxidation. , anti-cancer and other aspects have good effects. In terms of cancer treatment and prevention, tea polyphenol EGCG has shown certain curative effect in clinical tests and in vitro and in vivo cell experiments. In the clinical trial, 60 patients with precancerous lesions of prostate were divided into the control group and the medication gr...

Claims

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Application Information

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IPC IPC(8): A61K31/353A61P35/00
CPCA61K31/353
Inventor 罗可望黄卫人蔡志明
Owner THE SECOND PEOPLES HOSPITAL OF SHENZHEN
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