Individual biomimetic dental implant and making method thereof

Abstract

The invention relates to an individual biomimetic dental implant and a making method thereof, and the individual biomimetic dental implant includes an implant body imitating an original teeth root tissue structure of a missing tooth of a patient, a bionic artificial alveolar bone structure outer layer which is bonded with the outer surface of the implant body into one body, and biological protein molecule-bone morphogenetic protein (BMP) which is attached to the bionic artificial alveolar bone structure outer layer. The implant body and the bionic artificial alveolar bone structure outer layer are overall 3D-printed, and are similar to the original teeth root tissue structure and the alveolar bone tissue structure of the missing tooth of the patient, and the BMP-modified biological protein molecule promoting rapid bone formation is added, so that an ideal bionic artificial teeth root tissue structure is provided. The most important is to provide a good biological activity structure which is conducive to bone marrow stem cell and bone formation-related cell adhesion, proliferation and mineralization to finally play the osteogenic function, a bone formation promotion microenvironment is created, bone cell formation is induced, and early rapid and strong bone combination can be realized.

Description

technical field [0001] The invention belongs to a biomedical dental implant, in particular to an individualized bionic dental implant and a manufacturing method thereof. Background technique [0002] With the increase of traffic accidents and the acceleration of the aging process of society, the number of people with missing teeth is increasing year by year. With the improvement of people's living standards, people's requirements for the restoration of dentition defects and missing dentition are increasing. With the rapid development of implant technology, oral implants are increasingly widely used in the restoration of dentition defects and missing dentition to restore aesthetics and function. In the field of dental implants, pure titanium metal (or alloy) is widely used because of its good biocompatibility, mechanical properties and corrosion resistance. However, there are problems: most of the traditional titanium implants are fully dense, their elastic modulus is more ...

AI Technical Summary

Problems solved by technology

However, there are problems: most of the traditional titanium implants are fully dense, their elastic modulus is more than ten times that of natural bone, and their mechanical compatibility is poor. Occlusion, reducing the success rate and long-term life of the implant

The problem lies in: the surface coating of the substrate is uneven and the surface coating of the substrate with complex shapes cannot be processed; the processing temperature in the preparation is too high (10000 ° C), and the residual interfacial stress between the coating and the substrate during cooling causes the coating to loosen or peel off ; High temperature is easy to decompose HA to produce impurities such as amorphous HA, which affects the biological properties of the coating, etc.

Prolong the patient's treatment cycle, increase the patient's pain and treatment costs

[0017] 3) The lack of correct and effective guidance of the extraction socket for the direction of implant placement increases the complexity of the operation and the risk of damage to important structures such as nerves and blood vessels due to the deviation of the implant placement direction

It is not easy to obtain the ideal anatomical position, which affects the aesthetics and biomechanical compatibility of the later crown restoration

[0018] 4) The gingival papilla cannot be effectively preserved, which affects the aesthetic effect of implant denture restoration

[0019] 5) After tooth extraction, failure to repair immediately leads to the elongation and displacement of the opposing teeth and the oblique displacement of the adjacent teeth during the healing process of the extraction socket, which affects the later restoration effect

[0020] Fourth, most of the existing implants are imported, and a considerable part of the cost of implant restoration comes from the high cost of imported implant materials, resulting in high cost of implant restoration, which greatly increases the economic burden of patients and restricts the cost of implant restoration. The clinical further promotion of denture technology is difficult to benefit the majority of patients with missing teeth

In the process of promoting the development of domestic implants, the lack of strict implant quality control and the lack of diversified restoration options in the conventional assembly line production method have become bottlenecks restricting the development of domestic implants; making it difficult for domestic implants to obtain independent intellectual property rights Dominate the market

[0022] Fifth, the existing assembly line production methods of implants cannot meet the needs of individualized medical care and precision medicine in modern medicine, and are not conducive to the establishment of a harmonious doctor-patient relationship

[0025] The sand blasting acid etching and chemical processing methods

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