Monolayer molybdenum disulfide-cobalt ferrite nanocomposite material as well as preparation method and application thereof

Abstract

The invention discloses a monolayer molybdenum disulfide-cobalt ferrite nanocomposite material and a preparation method and application thereof, and particularly relates to the field of novel nanocomposite materials. The monolayer molybdenum disulfide-cobalt ferrite nanocomposite material consists of molybdenum disulfide nanonanosheets and cobalt ferrite nanoparticles, wherein the surfaces of the molybdenum disulfide nanonanosheets are uniformly modified by the cobalt ferrite nanoparticles; the molybdenum disulfide nanonanosheets adopt layered stripping structures. The cobalt ferrite nanoparticles are assembled on the surfaces of the molybdenum disulfide nanonanosheets through a reaction in which amino groups and carboxyl groups form amide bonds; the preparation method has the advantages of low energy consumption, low cost and high yield; the obtained composite material can be used as a magnetic resonance imaging contrast agent and a controllable medicine carrier at the same time; under the guidance of a magnetic field, a medicine can reach and be enriched on a lesion site so as to achieve intelligent medicine release and real-time therapeutic effect assessment under the guidance of magnetic resonance imaging; through change of the relative contents of molybdenum disulfide and cobalt ferrite in the composite material, controllable adjustment of the magnetic resonance imaging effect and the medicine loading capacity can be achieved.

Description

technical field

[0001] The invention relates to the field of novel nanocomposite materials, in particular to a single-layer molybdenum disulfide-cobalt ferrite nanocomposite material and its preparation method and application. Background technique

[0002] Magnetic resonance imaging has the biological safety of no radiation damage, the technical flexibility of tomography in any direction, and the technical advantages of covering multi-parameter characteristics such as proton density, relaxation, and chemical shift, as well as high spatial resolution and high contrast. It has become one of the most powerful detection methods in contemporary clinical diagnosis. Magnetic resonance imaging mainly realizes the spatial positioning of hydrogen protons in human tissue through the gradient magnetic field dependent on the spatial position, and then realizes human body imaging through the acquisition, processing and image reconstruction of hydrogen proton magnetic resonance signals. T...

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