Fracture healing simulation method based on biomechanical regulation algorithm
A fracture healing and simulation method technology, applied in the field of biomedical engineering, can solve problems such as failure to achieve fixator optimization, failure to simulate fractures, failure to simulate the influence of blood vessel fracture healing, etc.
Inactive Publication Date: 2017-04-05
HARBIN UNIV OF SCI & TECH
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Problems solved by technology
[0005] (1) The current model is too simplified. It only studies the fracture healing process of a single shape and a single part, and cannot simulate the healing of different types of fractures in different parts of specific patients.
[0006] (2) There are great restrictions on the selection of fixators. The existing model only simulates one fixation method, and cannot realize the optimization of fixators, which hinders doctors from providing better treatment options for patients.
[0007] (3) The current model only qualitatively describes the relationship between blood vessels and fracture healing, but fails to simulate the growth of blood vessels along with the fracture healing process and the impact of new blood vessels on fracture healing
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[0038] A fracture healing simulation method based on mechanobiological adjustment algorithm, the implementation process is as follows: figure 1 As shown, it specifically includes the following steps:
[0039] (1) Establish a three-dimensional geometric model of the fracture site;
[0040] 1) Obtain multiple images in DICOM format through CT of medical imaging equipment,
[0041] 2) Then import it into Mimics software for 3D reconstruction,
[0042] 3) Import the 3D reconstructed model into Geomagic software for smoothing and solidification operations to obtain a 3D geometric model of the fracture site.
[0043] (2) Carry out grid division with the geometric model that obtains, and set up the finite element model of bone and callus;
[0044] The obtained geometric model was imported into ANSYS for mesh division, and the finite element model of linear elastic bone and callus was established.
[0045] The ANSYS meshing process is as follows:
[0046] 1) Define unit propertie...
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The invention discloses a fracture healing simulation method based on a biomechanical regulation algorithm. The method specifically comprises the following steps: establishing a three-dimensional geometrical model of a fractured part; performing mesh generation on the obtained three-dimensional geometrical model, and establishing a bone and callus finite element model; setting a tissue type of the callus in an initial state; performing initial setting of simulation on the finite element model; computing deviator strain in the callus; simulating the growth of a blood vessel by utilizing a diffusion equation; and establishing a fracture healing simulation process based on the biomechanical regulation algorithm. According to the fracture healing simulation method based on the biomechanical regulation algorithm, by combining a deviator strain biological regulation algorithm with a blood vessel dynamic growth situation, a dynamic process of fracture healing can be accurately simulated.
Description
technical field [0001] The invention belongs to the field of biomedical engineering, and in particular relates to a fracture healing simulation method based on a mechanobiological adjustment algorithm. Background technique [0002] With the development of science and technology and the continuous progress of transportation, high-energy injuries are increasing day by day, and the incidence of fractures is increasing year by year. With the fractures becoming more serious and complicated, the treatment is more difficult and complicated. At the same time, postoperative fracture healing time is long, randomness is high, predictability is poor, and the progress is difficult to grasp, etc. are also medical problems. With the improvement of living standards, people's requirements for fracture treatment effects are also getting higher and higher, and the problem of improving medical standards needs to be solved urgently. Fractures are a high-incidence trauma. In countries with advan...
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Login to View More IPC IPC(8): G06F19/00G06F17/50
CPCG06F30/23G16H50/50
Inventor 王沫楠王新宇杨宁
Owner HARBIN UNIV OF SCI & TECH