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Norsampsone A-containing pharmaceutical composition for cervical cancer inhibition

A composition and cervical cancer technology, applied in the field of medicine, can solve problems such as NorsampsoneA and Taxifolin that have not been seen

Inactive Publication Date: 2017-04-19
徐州诺克非医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There is no report about Norsampsone A and Taxifolin inhibiting cervical cancer

Method used

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  • Norsampsone A-containing pharmaceutical composition for cervical cancer inhibition
  • Norsampsone A-containing pharmaceutical composition for cervical cancer inhibition

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Experimental program
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Embodiment Construction

[0011] The above description is only an overview of the technical solution of the present invention. In order to understand the technical means of the present invention more clearly and implement it according to the content of the description and conventional technical means in the field, the animal test examples of the present invention will be further described in detail below .

[0012] Chinese name: Taxifolin, CAS number: 480-18-2, Yunnan Xili Biotechnology Co., Ltd. and other companies are available for sale.

[0013] For the preparation method of the compound Norsampsone A involved in the present invention, please refer to the literature: Norsampsones A–D, Four New Decarbonyl Polycyclic Polyprenylated Acylphloroglucinols from Hypericum sampsonii, Org. Lett., 2014, 16 (13), 3448–3451. Publication Date (Web): June 16, 2014.

[0014] Drug efficacy test:

[0015] Modeling: female mice, weighing 20-24g, the ambient temperature of the animal room is 27°C-30°C, and the humidi...

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PUM

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Abstract

The present invention discloses a Norsampsone A-containing pharmaceutical composition for cervical cancer inhibition, wherein the effective components comprise Norsampsone A and taxifolin. According to the present invention, by the combined application of Norsampsone A and taxifolin, the experiment results show that the good cervical cancer inhibition effect is provided when the ratio of Norsampsone A to taxifolin is 10:1-12:1.

Description

technical field [0001] The invention relates to a pharmaceutical composition containing Norsampsone A for inhibiting cervical cancer, which belongs to the technical field of medicine. Background technique [0002] Cervical cancer refers to malignant tumors that occur in the uterine vagina and cervical canal. Cervical cancer metastasis can spread directly to adjacent tissues and organs, down to the vaginal fornix and vaginal wall, up to the uterus, to both sides of the pelvic cavity, forward to the bladder, and backward to the rectum. It can also be transferred to the paracervix, internal iliac, external iliac, and inguinal lymph nodes through lymphatic vessels, and can even be transferred to supraclavicular and other lymph nodes in the whole body in the late stage. Hematogenous metastasis is relatively rare, and the common metastatic sites are lung, liver and bone. Cervical cancer is one of the most common malignant tumors in gynecology. It is an important issue to find e...

Claims

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Application Information

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IPC IPC(8): A61K31/122A61K31/353A61P35/00
CPCA61K31/122A61K31/353
Inventor 庄焕迪
Owner 徐州诺克非医药科技有限公司