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Method for increasing reproductive rate of heterocephalus glabers

A technology of naked mole-rat and reproduction rate, applied in application, other equipment, animal husbandry, etc., can solve the problems of mutual bite, low reproduction efficiency, unable to reproduce normally, and achieve high pregnancy success rate, simple operation, and mating judgment. accurate effect

Active Publication Date: 2017-04-26
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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AI Technical Summary

Problems solved by technology

[0003] In the early stage, the laboratory adopts the original colony breeding method for reproduction. Each colony consists of about dozens of naked mole rats. Among them, only one female rat can reproduce, and the other female rats cannot reproduce. The reproductive efficiency of this reproductive method is very low, resulting in Naked mole rats have low reproductive capacity
However, in the early stage of breeding according to the closed group breeding method of mice, it was found that male and female mice of different litters would bite each other when they were caged together, and more than 1 / 3 of the paired individuals could not reproduce normally

Method used

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  • Method for increasing reproductive rate of heterocephalus glabers
  • Method for increasing reproductive rate of heterocephalus glabers

Examples

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Embodiment 1

[0025] 1) Primary screening of naked mole rat behavior:

[0026] Screen out the female naked mole rats that show mental malaise, reduced diet, and abnormal irritability within a period of 1-3 days; during the non-estrous period, the living conditions of female naked mole rats have no characteristics to follow;

[0027] 2) Re-screening of naked mole rat vulva status

[0028] The light red horizontal bar-shaped gap between the anus and the outside of the urethra of the female naked mole rats screened in step 1) was detected, and there was a light red horizontal bar-shaped gap between the anus and the outside of the urethra of the non-estrous female rats ( figure 1 a), the color of the crossbar in the female mouse in estrus is darkened, the gap is opened, and obvious redness and swelling can be seen, forming two raised petals, and there are transparent liquid adhesions ( figure 1 b);

[0029] 3) Vaginal smear test

[0030] Smear the cervical mucus of the individual female nake...

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Abstract

The invention relates to the technical field of animal reproduction, in particular to a method for increasing the reproductive rate of heterocephalus glabers. According to the method, behavioristics observation, cunnus state observation and vaginal smear detection are conducted on the heterocephalus glabers, and whether the heterocephalus glabers are in the oestrum or not is judged accurately; and furthermore, the male heterocephalus glabers of the same cage source are selected to be put into a rearing cage of the female heterocephalus glabers, cage combination is conducted according to the proportion of one to one, copulatory behavior observation is conducted, and thus the purpose of identifying whether the male heterocephalus glabers copulate with the female heterocephalus glabers or not is achieved. The reproduction method is easy to operate, accurate in oestrum and copulation judgment and high in gestation success rate of the heterocephalus glabers.

Description

technical field [0001] The invention relates to the technical field of animal reproduction, in particular to a method for improving the reproductive rate of naked mole rats. Background technique [0002] Naked mole rats are the only mammals found so far that have a social life like bees, ants and other insects. In a colony, only one female naked mole rat and 1-3 male rats are in a dominant position and can reproduce offspring. The camp-social reproduction mode of naked mole rats is not conducive to the genetic quality control of naked mole rats, and also restricts the establishment of closed populations and inbred populations of naked mole rats. In order to establish a standardized experimental animal population, the research team tried to break the reproductive mode of naked mole rats in a true social community, and established a reproductive mode of mating at a ratio of 1:1 male to female (female rats are over 10 months old, and males are over 12 months old). This breedin...

Claims

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Application Information

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IPC IPC(8): A01K67/02A01K29/00
CPCA01K29/005A01K67/02
Inventor 崔淑芳赵善民孙伟林丽芳刘攀徐晨余琛琳蔡丽萍
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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