System and method for using computational fluid mechanics to simulate and calculate fractional blood flow reserve

Abstract

The invention provides a system and method for using computational fluid mechanics to simulate and calculate fractional blood flow reserve. The system comprises a vascular tree model generation module, a computational grid generation module, a boundary condition setting module, an attribute setting module, a solver and an aftertreatment module, wherein the vascular tree model generation module acquires a medical image, executes segmentation and reestablishes a geometric model of a vascular tree of an individual, the computational grid generation module generates a computational grid for the geometric model and establishes a CFD model of the vascular tree, the boundary condition setting module sets corresponding inlet and outlet boundary conditions for the CFD model of the vascular tree, the attribute setting module sets the physical property and a flow equation of blood, the solver seeks solutions on the CFD model of the vascular tree based on the inlet and outlet boundary conditions so as to obtain fluid parameters around the vascular tree, the set physical property and the flow equation, and the aftertreatment module conducts aftertreatment on the fluid parameters so as to obtain the fractional blood flow reserve, and both the inlet boundary condition and outlet boundary condition have individual specificity. According to the system and method for using computational fluid mechanics to simulate and calculate the fractional blood flow reserve, the accuracy of a simulation result is guaranteed, and the calculation time acceptable to clinics can be achieved at the same time.

Description

technical field [0001] The present invention relates to a system and method for calculation and analysis of human physiology and hemodynamics, more specifically to a system for applying computational fluid dynamics (CFD) to simulate and calculate fractional blood flow reserve, and for computational fluid dynamics (CFD) of vascular trees ( CFD) model to set the corresponding inlet boundary conditions and outlet boundary conditions. Background technique [0002] The main cause of coronary heart disease is coronary artery stenosis caused by arteriosclerosis. Coronary stenosis can cause major changes in coronary blood flow and other hemodynamics, causing relative and absolute myocardial ischemia. Coronary angiography and intravascular ultrasonography are considered to be the "gold standard" for the diagnosis of coronary heart disease, but they can only perform imaging evaluation on the degree of stenosis, but the impact of stenosis on distal blood flow (functional evaluation) c...

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Problems solved by technology

The boundary conditions set based on this assumption or statistics cannot reflect the specificity of individuals, which affects the accuracy of simulation calculations

In addition, in order to automatically and accurately predict the fluid parameters of clinically concerned vascular branches, existing vascular computing systems usually need to perform CFD modeling and calculation of the relevant entire vascular tree (such as the entire vascular tree of the coronary artery), which takes a long time. , and consumes a lot of computing resources, which hinders its clinical promotion

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