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Traditional Chinese medicine composition with anti-depression effect and preparation method thereof

A technology of composition and traditional Chinese medicine, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., to achieve the effect of smooth qi and blood and balance of yin and yang

Inactive Publication Date: 2017-06-09
JIUZHITANG +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the etiology of depression has not yet been determined, and it is related to many factors such as biology, psychology, and social environment. The existing treatment drugs include western medicine fluoxetine, fluvoxamine, etc., and traditional Chinese medicines include Danzhi Xiaoyao powder, Jieyu pill, etc.

Method used

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  • Traditional Chinese medicine composition with anti-depression effect and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] (1) Weigh the raw materials of Bupleurum, Chinese Angelica, Radix Paeoniae Alba, Tangerine Peel, Rhizoma Chuanxiong, and Radix Glycyrrhizae according to the following parts by weight:

[0022] Bupleurum 120g Angelica 100g White Peony 100g

[0023] Chenpi 80g Chuanxiong 20g Licorice (honey roasted) 80g

[0024] Take the above six flavors, crush them into fine powder, add 75% ethanol to extract twice, each time for 2 hours, add 8 times of ethanol each time, combine the extracts, filter, concentrate to 1.24-1.26 (65°C) clear paste, microwave drying ,spare;

[0025] (2) Take the dry paste powder, microcrystalline cellulose, hydroxypropyl cellulose, and crospovidone, mix them evenly with the clear paste obtained in step (1), add ethanol solution to granulate, dry at 60-80°C, and granules, add magnesium stearate, mix evenly, and compress into tablets.

Embodiment 2

[0027] (1) Weigh the raw materials of Bupleurum, Chinese Angelica, Radix Paeoniae Alba, Tangerine Peel, Rhizoma Chuanxiong, and Radix Glycyrrhizae according to the following parts by weight:

[0028] Bupleurum 140g Angelica 120g White Peony 120g

[0029] Chenpi 60g Chuanxiong 30g Licorice (honey roasted) 60g

[0030] Take the above six flavors, grind them into fine powder, add 80% ethanol to extract twice, each time for 1 hour, add 10 times the amount of ethanol each time, combine the extracts, filter, concentrate to 1.24-1.26 (65°C) clear paste, microwave dry, ready for use;

[0031] (2) Take the dry paste powder, microcrystalline cellulose, hydroxypropyl cellulose, and crospovidone, mix them evenly with the clear paste obtained in step (1), add ethanol solution to granulate, dry at 60-80°C, and granules, add magnesium stearate, mix evenly, and compress into tablets.

Embodiment 3

[0033] (1) Weigh the raw materials of Bupleurum, Chinese Angelica, Radix Paeoniae Alba, Tangerine Peel, Rhizoma Chuanxiong, and Radix Glycyrrhizae according to the following parts by weight:

[0034] Bupleurum 100g Angelica 80g White Peony 80g

[0035] Chenpi 100g Chuanxiong 10g Licorice (honey roasted) 100g

[0036] Take the above six flavors, crush them into fine powder, add 60% ethanol to extract twice, each time for 2 hours, add 6 times of ethanol each time, combine the extracts, filter, concentrate to 1.24-1.26 (65°C) clear paste, microwave drying ,spare;

[0037] (2) Take the dry paste powder, microcrystalline cellulose, hydroxypropyl cellulose, and crospovidone, mix them evenly with the clear paste obtained in step (1), add ethanol solution to granulate, dry at 60-80°C, and granules, add magnesium stearate, mix evenly, and compress into tablets.

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Abstract

The invention provides a traditional Chinese medicine composition with anti-depression effect. The traditional Chinese medicine composition is prepared from the following crude drugs of radix bupleuri, Chinese angelica, radix paeoniae alba, dried tangerine peel, rhizoma chuanxiong, liquorice root and the like. The invention also provides a preparation method of the medicine composition.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition prepared from Bupleurum radix and Angelica sinensis for preventing and treating depression and a preparation method thereof. Background technique [0002] Depression is a common mental disorder. Worldwide, more than 350 million people of all ages suffer from depression. Depression is characterized by sadness, loss of fun, sluggish thinking, listlessness, social withdrawal, and even pessimism and suicidal thoughts or behaviors. At present, the cause of depression has not been determined, and it is related to many factors such as biology, psychology, and social environment. The existing therapeutic drugs include western medicines such as fluoxetine and fluvoxamine, and traditional Chinese medicines include Danzhi Xiaoyao San and Jieyu Pills. [0003] Depression can be...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P25/24
Inventor 卢捷谷陟欣李伟黄胜颜冬兰王芝华
Owner JIUZHITANG
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