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Chinese composition for preventing and treating duck virus hepatitis

A technology for duck viral hepatitis and composition, applied in the directions of antiviral agents, applications, animal feed, etc., can solve the problems of easy recurrence, inability to cure, contaminate pathogenic microorganisms, etc., achieves no toxic side effects, balances yin and yang, and has a high cure rate. Effect

Inactive Publication Date: 2012-07-04
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

High-immune yolk antibodies have the disadvantage of being difficult to preserve. Sometimes repeated injections of high-immune yolk antibodies are difficult to control the disease. Moreover, most of the production of yolk antibodies does not use duck eggs produced by SPF (specific pathogenic microorganism-free) ducks. , thus causing pathogenic microorganisms to be transmitted to ducks through yolk antibodies. Even if duck eggs produced by SPF ducks are used, because yolk itself is a kind of nutrient substance, if you do not pay attention to aseptic operation or improper storage during production, it is very easy to contaminate pathogenic microorganisms. cause the spread of disease
Hyperimmune serum and monoclonal antibodies are rarely used due to their high price and shortage of supply
[0006] In addition, there are few Chinese veterinary medicines on the market that can treat duck hepatitis. Even if some species can prevent and treat duck hepatitis, there are disadvantages that are easy to relapse and cannot be cured.

Method used

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  • Chinese composition for preventing and treating duck virus hepatitis

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Effect test

preparation example Construction

[0084] The present invention also provides the preparation method of the above-mentioned traditional Chinese medicine composition for preventing and treating duck viral hepatitis, which comprises:

[0085] In the first step, each component is mixed and pulverized according to the stated ratio;

[0086] In the second step, the pulverized mixture obtained in the first step is added to ethanol and heated to reflux for extraction, the extracts are combined, centrifuged, and filtered to obtain a purified ethanol extract;

[0087] The third step is to obtain the Chinese medicine extract by evaporating the ethanol in the ethanol extract in the second step;

[0088] The fourth step is to dissolve the Chinese medicine extract obtained in the third step in deionized water, use macroporous adsorption resin to absorb and recover the Chinese medicine extract, and then elute it with deionized water;

[0089] The fifth step is to use distillation to evaporate the water in the product obtain...

Embodiment 1

[0115] Embodiment 1 The acute toxicity test of Chinese medicine composition of the present invention to duckling

[0116] 1. Test animals

[0117] 50 3-day-old Mianyang ducklings without maternal antibodies, half male and half male, weighing 20-25g; purchased from Mianyang Duck Breeding Center

[0118] 2. Test drug

[0119]50g Dandelion, 25g Folium Folium, 12g Qinpi, 13g Quanshen, 8g Anemarrhena, 17g Chishao, 10g Scutellaria, 12g Gardenia, 6g Yin Bupleurum, 4g Fangfeng, 20g Codonopsis, 7g Chinese Yam, 15g Angelica, 6g Licorice , 10g rehmannia glutinosa, 6g donkey-hide gelatin, 15g gastrodia elata, 12g uncaria and 6g ocher were mixed and crushed; then 650g mass percentage concentration of 95% ethanol was added and heated and refluxed for 3 times, and the heating and reflux time was 2 hours each time, and the extracts were combined , centrifuged and filtered to obtain a purified ethanol extract; evaporate the ethanol in the ethanol extract in the second step to obtain a Chines...

Embodiment 2

[0144] Embodiment 2 The long-term toxicity test of Chinese medicine composition of the present invention to duckling

[0145] Take 10 ducklings, with a body weight of 20-25g, half male and half male, long-term administration for 3 weeks, and carry out long-term toxicity test. Abnormal changes were seen, and no pathological changes were found in histopathology and autopsy.

[0146]

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Abstract

The invention provides a Chinese composition for preventing and treating duck virus hepatitis, which comprises dandelion, folium isatidis, ash bark, adder-wort, rhizoma anemarrhenae, radix paeoniae rubra, scutellaria baicalensis, jasmine, radices stellariae dichotomae, divaricate saposhnikovia root, codonopsis pilosula, Chinese yam, angelica sinensis, liquorice, radix rehmanniae praeparata, donkey-hide gelatin, gastrodia elata, uncaria rhynchophylla and ochre. The Chinese composition has remarkable curative effects on prevention and treatment of the duck virus hepatitis suffered by duckling and has the advantages of treating both principal and secondary aspects of diseases, strengthening body resistance and eliminating evil, adjusting overall aspects, balancing yin and yang, and being high in curative rate, free of toxic and side effects, not easy to relapse, free of medicine damage, low in cost and the like.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese veterinary medicine, in particular to a traditional Chinese medicine composition for preventing and treating duck viral hepatitis. [0002] Background technique [0003] Duck virus hepatitis (DVH), referred to as duck hepatitis, is an acute, highly contagious and fatal infectious disease of ducklings caused by duck virus hepatitis virus. Mainly characterized by hepatitis. Since the disease was first reported on Long Island in the United States in 1950, it has successively occurred in the United Kingdom, Canada, Germany, Italy, India, France and other places. Up to now, the disease has almost spread to most duck-raising countries and regions in the world. In my country, the disease has also been found in places such as Songming County in Yunnan, Wenzhou in Fujian, Shijiazhuang in Hebei, and Yuyao County in Zhejiang. Duck viral hepatitis can occur throughout the year. Natural outbreak...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61P31/14A23K1/16A23K1/18
Inventor 邹明郝智慧路平
Owner QINGDAO AGRI UNIV
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