Z-type simple parallel plate flow chamber

A parallel plate, flow chamber technology, applied in the field of cell biomechanics, can solve problems such as the inability to provide a sufficiently high effective area ratio, the location of the shear stress field is unclear, and the failure of cell biomechanics experiments, so as to reduce the entrance and exit effects. , Improve the effective area ratio, the effect of fluid shear stress uniformity

Inactive Publication Date: 2017-06-09
BEIHANG UNIV
View PDF1 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The position of the shear stress field in the existing simple parallel plate flow chamber is unclear and cannot provide a high enough effective area ratio characteristic, resulting in the failure or failure of many cell biomechanical experiments
[0003] The Chinese patent

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Z-type simple parallel plate flow chamber
  • Z-type simple parallel plate flow chamber
  • Z-type simple parallel plate flow chamber

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0025] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention more clear, the following drawings and embodiments describe the technical solutions according to the present invention. It should be understood that the following examples are used to illustrate the present invention, but not to limit the scope of the present invention. The drawings and written description are not intended to limit the scope of the inventive concept in any way but to illustrate the inventive concept for those skilled in the art by reference to specific embodiments.

[0026] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", "vertical", "inner" and "outer" are based on The orientation or positional relationship shown in the drawings is only for the convenience of describing the present invention and simplifying the description, an...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a Z-shaped simple parallel plate flow chamber, which includes a bottom plate, a cover plate and a glass slide. The bottom plate is provided with a glass slide slot and an observation hole, and the cover plate is provided with an entrance and exit and an entrance and exit buffer groove. The level of the buffer platform at the entrance and exit of the slide is higher than the effective area of ​​the slide, and the entrance and exit of the cover plate are perpendicular to the groove surface of the entrance and exit buffer tank, so that the fluid pressure will not directly act on the entrance and exit structure. The flow in the effective action area of ​​the slide is stable, the effective action area is defined, and the effective action area ratio is improved. The fluid shear stress received by the cells in the effective action area of ​​the slide is very uniform, which weakens the inlet and outlet effects of the parallel plate flow chamber. It can meet the needs of cell biomechanical experimental research, and by adjusting the inlet flow, the fluid shear stress can be regulated.

Description

technical field [0001] The invention belongs to the field of cell biomechanics research, and in particular relates to a mechanical loading experiment device for in vitro culture of isolated cells. Background technique [0002] Due to the complexity of the physiological structure of biological tissues and organs and the diversity of physiological environments in living organisms, the physiological and mechanical environments in which somatic cells live are also intricate. With the development of in vitro culture and isolation technology of cells, it has become an effective and popular experimental method to conduct cell-level experiments under controlled conditions in vitro. The simple parallel plate flow chamber is an in vitro cell culture device that uses the flow of culture liquid to generate shear stress to act on the cell surface. It is used to study the changes in the shape, adhesion and function of cells under different shear forces. It is one of the main experimental...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C12M3/00
CPCC12M35/04
Inventor 樊瑜波李莹储照伟郭萌
Owner BEIHANG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap