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Biochemical extraction process of naringin and use of its extract in treating dermatitis

An extraction process, the technology of naringin, applied in the field of biochemical extraction, can solve the problems of not being suitable for industrial production, low extraction efficiency, easy to pollute the environment, etc., and achieve the effect of increasing the leaching rate, increasing the yield and purity, and improving the extraction efficiency

Active Publication Date: 2019-04-19
李潇
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The hot water extraction method has many impurities, low extraction efficiency, serious waste of water resources and other defects; the alkali extraction and acid precipitation method has the advantages of saving economy and simple process, but its reaction time is long and it is easy to pollute the environment, so it is not suitable for industrial production
Zhou Shilei, Chinese Journal of Agricultural Engineering, 2006, research on the ethanol extraction process of naringin from pomelo peel, using alcohol extraction, the extraction rate can reach 91%, but there are defects such as low purity and a large amount of ethanol consumption

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The biochemical extraction process of naringin, it comprises the steps:

[0027] Take fresh, mildew-free pomelo peel, dry it at 50°C until the moisture content is less than 3 wt%, pulverize it in a pulverizer, pass through a 100-mesh sieve, collect the pomelo peel powder, and then add it to the same weight of 30g / L sucrose In the aqueous solution, stir at 300rpm for 10 hours, then let it stand for 6 hours, dry it at 50°C, put it in the reaction kettle, control the pressure in the reaction kettle to 1.2MPa, the temperature is 120℃, keep the heat and pressure for 5min, and after cooling to room temperature, then Add 0.4g / L calcium hydroxide aqueous solution accounting for 5 times the weight of pomelo peel powder and cellulase (20000u / g) accounting for 0.07wt% pomelo peel powder, stir at 300rpm for 6h, and then let stand for 30min; centrifuge to collect the precipitate , add twice the mass of 70% (v / v) ethanol to the precipitate, heat in a water bath at 60°C, stir for 30 m...

Embodiment 2

[0029] The biochemical extraction process of naringin, it comprises the steps:

[0030] Take fresh, mildew-free pomelo peels, dry them at 50°C until the moisture content is less than 3 wt%, pulverize them in a pulverizer, pass through a 100-mesh sieve, collect pomelo peel powder, and then add it to the same weight of 40g / L sucrose In the aqueous solution, stir at 500rpm for 8 hours, then let it stand for 6 hours, dry it at 50°C, put it in the reaction kettle, control the pressure in the reaction kettle to 1.0MPa, the temperature is 130℃, keep the heat and pressure for 5min, after cooling to room temperature, then Add 0.6g / L calcium hydroxide aqueous solution accounting for 5 times the weight of pomelo peel powder and cellulase (20000u / g) accounting for 0.05wt% of pomelo peel powder, stir at 300rpm for 6h, and then let it stand for 30min; centrifuge to collect the precipitate , add twice the mass of 70% (v / v) ethanol to the precipitate, heat in a water bath at 60°C, stir for 30...

Embodiment 1-2

[0032] Example 1-2 extraction method of the present invention obtains product purity and yield detection:

[0033] Taking Anjiang pomelo as an example, the purity of naringin in the product and the yield of naringin were determined by HPLC; the calculation of the yield of naringin: the yield of naringin=((quality of naringin product×purity ) / pomelo peel powder mass)×100%; the specific results are shown in Table 1:

[0034] Table 1

[0035] index

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PUM

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Abstract

The invention relates to the technical field of biochemical extraction, and discloses a biochemical extraction technology of naringin. The technology comprises the following steps: 1, drying and crushing; 2, sucrose processing; 3, high temperature and high pressure treatment; 4, alkali liquid and enzyme treatment; and 5, alcohol dissolving, temperature control and water extraction. The extraction technology is optimized through adopting multifactorial quadrature test, so the yield and the purity are improved; and the prepared product can effectively treat the dermatitis.

Description

technical field [0001] The invention relates to the technical field of biochemical extraction, in particular to a biochemical extraction process of naringin and the use of its extract in treating dermatitis. Background technique [0002] Naringin is a flavonoid compound. Since there is no conjugation between ring A and ring B, there is a strong ultraviolet absorption peak at 282nm, which makes naringin display various biological activities and pharmacological effects. It has anti-inflammatory, anti-virus, anti-cancer, anti-mutation, anti-allergic, anti-ulcer, analgesic, and blood pressure-lowering activities, can lower blood cholesterol, reduce the formation of thrombus, improve local microcirculation and nutrient supply, and can be used for production and prevention of heart and brain vascular disease. Naringin is used as a natural pigment, flavor improver and bittering agent in the production of food and beverages, and can also be used as a new type of sweetener dihydron...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07H17/07C07H1/08A61P17/00
CPCC07H1/08C07H17/07
Inventor 李潇
Owner 李潇
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