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Application of rhizoma chuanxiong essential oil in preparation of medicine for treating rheumatoid arthritis and in preparation of joint protection health care product

A technique of chuanxiong essential oil and rheumatoid, applied in the field of pharmacy, can solve the problems of involuntary treatment, high cost and increase the economic cost of treatment of patients, etc., and achieve the effect of good treatment effect

Inactive Publication Date: 2017-07-25
四川九渊医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Existing treatments for rheumatoid arthritis are mainly through surgery, acupuncture, moxibustion, etc., but because these methods require professionals to operate, patients can only go to the hospital for medical treatment, and cannot perform independent treatment at home. At the same time, the traditional The high cost of the treatment method increases the economic cost of the patient's treatment

Method used

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  • Application of rhizoma chuanxiong essential oil in preparation of medicine for treating rheumatoid arthritis and in preparation of joint protection health care product
  • Application of rhizoma chuanxiong essential oil in preparation of medicine for treating rheumatoid arthritis and in preparation of joint protection health care product

Examples

Experimental program
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Effect test

Embodiment 1

[0030] The initial essential oil of Chuanxiong was obtained through the following steps: crush 1Kg of Chuanxiong with a particle size of 5 mm, then mix it with 1Kg of deionized water, and wet the 1Kg of Chuanxiong for 13 hours. Continuously pass the water vapor at 150°C slowly through the wet Rhizoma Chuanxiong, and then condense the mixed steam passing through the wet Rhizoma Chuanxiong to obtain an oil-water mixture, and use a separatory funnel to separate the oil from water to obtain the essential oil of Rhizoma Chuanxiong. Since the components of the Chuanxiong essential oil extracted by the above method cannot be consistent with the precise values ​​required by the experimenter, pure ligustilide, pure cnidactone A and pure neocnilide were used in the examples. To adjust the extracted Chuanxiong essential oil, the adjusted Chuanxiong essential oil includes 10% ligustilide, 6% cnidactone A and 13% cnidactone, and the remaining components are other esters.

Embodiment 2

[0032] The initial essential oil of Chuanxiong was obtained through the following steps: crush 0.9Kg of Chuanxiong with a particle size of 6 mm, then mix it with 0.45Kg of deionized water, and wet the 0.9Kg of Chuanxiong for 7 hours. Continuously pass the water vapor at 170°C slowly through the wet Rhizoma Chuanxiong, and then condense the mixed steam passing through the wet Rhizoma Chuanxiong to obtain an oil-water mixture, and use a separatory funnel to separate the oil from water to obtain the essential oil of Rhizoma Chuanxiong. Since the components of the Chuanxiong essential oil extracted by the above method cannot be consistent with the precise values ​​required by the experimenter, pure ligustilide, pure cnidactone A and pure neocnilide were used in the examples. To adjust the extracted Chuanxiong essential oil, the adjusted Chuanxiong essential oil includes 15% ligustilide, 7% cnidactone A and 12% cnidactone, and the remaining components are other esters.

Embodiment 3

[0034]The initial essential oil of Chuanxiong was prepared by the following steps: 1.1Kg of Chuanxiong was pulverized to a particle size of 7mm, and then mixed with 0.33Kg of deionized water, and 1.1Kg of Chuanxiong was wetted for 20 hours. Continuously pass the water vapor at 200°C slowly through the wet Rhizoma Chuanxiong, and then condense the mixed steam passing through the wet Rhizoma Chuanxiong to obtain an oil-water mixture, and use a separatory funnel to separate the oil from water to obtain the essential oil of Rhizoma Chuanxiong. Since the components of the Chuanxiong essential oil extracted by the above method cannot be consistent with the precise values ​​required by the experimenter, pure ligustilide, pure cnidactone A and pure neocnilide were used in the examples. To adjust the extracted Chuanxiong essential oil, the adjusted Chuanxiong essential oil includes 20% ligustilide, 8% cnidactone A and 11% cnidactone, and the remaining components are other esters.

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Abstract

The invention provides novel application of rhizoma chuanxiong essential oil in the pharmaceutical field, and particularly relates to application of the rhizoma chuanxiong essential oil in preparation of a medicine for treating rheumatoid arthritis and in preparation of a joint protection health care product. The rhizoma chuanxiong essential oil can effectively improve the related physical and chemical properties of synovial fluid and blood and improve symptoms, such as swelling pain, malformation and inflammation, of a patient. The rhizoma chuanxiong essential oil can effectively treat the rheumatoid arthritis and also be used as the health care product for protecting joints. The rhizoma chuanxiong essential oil is convenient to prepare and use; the patient can use the rhizoma chuanxiong essential oil conveniently, and the rhizoma chuanxiong essential oil is low in toxic and side effect.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to the application of Chuanxiong essential oil in the preparation of medicines for treating rheumatoid arthritis and health care products for protecting joints. Background technique [0002] Rheumatoid arthritis (RA) is a chronic, inflammatory synovitis-based systemic disease of unknown etiology. It is characterized by polyarticular, symmetrical, and aggressive arthritis of the small joints of the hands and feet, often accompanied by involvement of extra-articular organs and positive serum rheumatoid factor, which can lead to joint deformities and loss of function. The pathogenesis of RA may be related to heredity, infection, and sex hormones. The pathology of RA arthritis mainly includes the proliferation of synovial lining cells, the infiltration of a large number of inflammatory cells in the interstitium, the neogenesis of microvessels, the formation of pannus, and the destruction of car...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/236A61P29/00A61P19/02
CPCA61K36/236A61K2236/331
Inventor 曹远东
Owner 四川九渊医药科技有限公司
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