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Systems and methods for optimizing transcranial acoustic therapy

An ultrasound therapy, transcranial technology, applied in ultrasound therapy, instruments for radiological diagnosis, treatment, etc., can solve problems such as limiting the effectiveness and efficiency of transcranial ultrasound therapy

Active Publication Date: 2019-08-30
INSIGHTEC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although conventional methods can partially improve ultrasound focusing, predicting the effect on the ultrasound beam passing through the skull is challenging due to the nature of the skull and its multilayered interior, which varies from patient to patient; this limits the use of Effectiveness and Efficiency of Traditional Approaches to Transcranial Ultrasound Therapy
Therefore, patients with cranial structures that result in poor ultrasound focusing properties may gain limited benefit from ultrasound therapy following safety standards that limit deliverable energy levels

Method used

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  • Systems and methods for optimizing transcranial acoustic therapy
  • Systems and methods for optimizing transcranial acoustic therapy
  • Systems and methods for optimizing transcranial acoustic therapy

Examples

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Embodiment Construction

[0043] figure 1 An exemplary ultrasound therapy system 100 is shown for focusing ultrasound waves to a patient's brain via the cranium. The system 100 includes a phased array 102 of transducer elements 104, a beamformer 106 to drive the phased array 102, a controller 108 in communication with the beamformer 106, and a frequency generator 110 to provide an input electronic signal to the beamformer 106 . In various embodiments, the system also includes an imager 112, such as a magnetic resonance imaging (MRI) device, a computed tomography (CT) device, a positron emission tomography (PET) device, a single photon emission computed tomography (SPECT) device, or ultrasonography device, for determining the anatomical properties of the skull 114 of the patient 116.

[0044] Array 102 may have a curved (eg, spherical or parabolic) shape suitable for placement on the surface of skull 114, or may include one or more planar or other shaped segments. Their dimensions can vary between a ...

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Abstract

Cranial bone inhomogeneity can be quantified based on cranial bone density measured in skull images acquired using conventional imagers; quantified inhomogeneity can then be used to determine whether a patient is suitable for ultrasound therapy and / or to determine optimal transcranial ultrasound A parameter of therapy associated with an ultrasound transducer.

Description

technical field [0001] The present invention relates generally to acoustic energy therapy and more particularly to systems and methods for optimizing acoustic energy delivery through non-uniform tissue, such as the skull, during therapy. Background technique [0002] Acoustic energy such as ultrasound penetrates soft tissue well and, due to its short wavelength, can be focused to a spot with a size of a few millimeters. Because of these properties, acoustic energy can and has been used for a variety of diagnostic and therapeutic medical purposes, including ultrasound imaging and non-invasive surgery of many parts of the body. For example, by heating diseased (eg, cancerous) tissue using ultrasound, it is often possible to ablate the diseased portion without causing significant damage to surrounding healthy tissue. [0003] The non-invasive nature of ultrasound surgery is particularly attractive for the treatment of brain tissue. Furthermore, coherent non-invasive focusing ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61N7/02A61B5/055A61B6/03A61B8/08
CPCA61B5/0042A61B5/055A61B6/032A61B6/037A61B6/501A61B6/5217A61B8/5223A61N7/02A61B8/0808A61N2007/0095A61N2007/025A61N2007/0021A61N2007/0078A61B2090/067A61B90/10A61B2090/062A61B2034/105A61B34/10A61B2034/104G16H50/30A61B8/0816A61N7/00
Inventor T·特勒斯蒂S·维塔克E·扎迪卡里奥
Owner INSIGHTEC
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