A marker capable of developing degraded stents under X-rays and a preparation method thereof
A technology of marking and stent mesh, applied in the field of medical devices, can solve the problems of large corrosion potential difference, corrosion of metal stents, inability to separate, etc., and achieves the effect of solving the contact potential difference, improving biocompatibility, and good medical safety.
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Embodiment 1
[0034] In this embodiment, the in vitro imaging effect of its imaging marks under medical X-rays refers to Figure 1~2 .figure 1 The surface treatment temperatures (from left to right) of the four developing bodies in the lower half shown are 300°C, 400°C, 700°C and 800°C, respectively. The thickness of the marking material is 0.040mm. The development marks of four conditions all performed well in the development effect of medical X-ray (see figure 2 ). The test results of its resistance show that except the resistance of the 300°C sample is small, the resistance values of the other three samples are all infinite. After XRD analysis of the above four samples, the results show that the 800°C sample contains a large amount of Ta 5 o 2 . It is actually a white powdery substance on the surface (see figure 2 , visible to the naked eye). The developing marking material obtained in the interval between 400°C and 700°C is a better choice in the present invention. The diame...
Embodiment 2
[0037] In this embodiment, the development effect of the large animal experiment in vivo under the medical X-ray is referred to Figure 4 . In this embodiment, the iliac artery of the experimental animal pig is used as the experimental blood vessel, and the processing method of the stent and the production process of the imaging mark are as described in Embodiment 1. The difference is that the surface of the stent in this implementation is sprayed with drug coating. The thickness of the stent mesh is 0.130mm, and the diameter of the developing mark is 0.38mm, and the thickness is between 0.095mm and 0.105mm. In this embodiment, the average thickness of the oxygen-rich layer of the developed mark is about 350 nm.
[0038] In order to compare the developing effects, this embodiment verifies the developing effects of adding developing marks at two positions. One is to set only one reserved hole at both ends of the bracket. The plane formed by the straight line passing through...
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