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Vertebral artery stent and manufacturing method thereof

A production method and technology of vertebral artery, applied in the field of medical devices, can solve the problem of high restenosis rate, achieve the effect of enhancing the ability of controlled release, preventing restenosis, and reducing the amount of drugs used

Inactive Publication Date: 2017-08-18
MICROPORT NEUROTECH SHANGHAI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The object of the present invention is to provide a vertebral artery stent and a manufacturing method thereof, so as to solve the problem of high restenosis rate in existing stents for vertebral arteries

Method used

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  • Vertebral artery stent and manufacturing method thereof
  • Vertebral artery stent and manufacturing method thereof
  • Vertebral artery stent and manufacturing method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0049] This embodiment provides a vertebral artery stent, the vertebral artery stent includes a plurality of unit ring structures 10, a plurality of connecting structures 20 and a drug coating 30, wherein: a plurality of the unit ring structures 10 are arranged axially, and a plurality of The connection structure 20 connects a plurality of the unit ring structures 10 to form a columnar structure; the drug coating 30 is only coated on the outer surface of the columnar structure, and the drug coating contains anti-stenosis drug components . Each of the unit ring structures 10 includes a plurality of ring end structures 11 and a plurality of straight rod structures 12, wherein: each of the ring end structures 11 is respectively connected to two of the straight rod structures 12 through two transition structures 14 In between, the two straight rod structures form an approximately "V"-shaped structure, and a plurality of the approximately "V"-shaped structures are arranged along th...

Embodiment 2

[0059] This embodiment provides a method for manufacturing a vertebral artery stent. The method for manufacturing a vertebral artery stent includes: forming a plurality of unit ring structures 10, arranging the plurality of unit ring structures 10 axially, and connecting a plurality of connecting structures 20 The unit ring structure 10 is to form a net column structure; a solution containing anti-stenosis drug components is prepared, and the solution is only coated on the outer surface of the net column structure to form a drug coating.

[0060] Specifically, each unit ring structure 10 is formed by the following method: providing a plurality of ring end structures 11 and a plurality of straight rod structures 12; connecting each ring end structure 11 to two straight rod structures through two transition structures 14 Between the structures 12, so that the two straight rod structures 12 form an approximately "V"-shaped structure, and a plurality of the approximately "V"-shaped...

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Abstract

The invention provides a vertebral artery stent and a manufacturing method thereof. The vertebral artery stent comprises multiple unit ring structures, multiple connection structures and a medicament coating. The multiple unit ring structures are arrayed in an axial direction. The multiple connection structures are connected to the multiple unit ring structures to form a net-post-shaped structure. The medicament coating is only coated on the outer surface of the net-post-shaped structure. The medicament coating contains anti-stenosis medicament components. The vertebral artery stent and the manufacturing method thereof have the following beneficial effects: by coating the medicament coating on the outer surface of the net-post-shaped structure, anti-stenosis medicament can be released by the medicament coating as compared with a conventional bare metal support used for vertebral artery so that restenosis is effectively prevented; in addition, the medicament coating is only coated on the outer surface of the net-post-shaped structure; compared with an intravascular stent with inner and outer sides having coatings or the overall coating, the control releasing capability of medicament is enhanced by a single-layer coating; adverse effect of medicament is reduced; and treatment efficiency of medicament is improved.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a vertebral artery stent and a manufacturing method thereof. Background technique [0002] Atherosclerosis in the vertebral-basilar artery system is one of the main causes of posterior circulation stroke, and about one-fifth of posterior circulation stroke occurs in the extracranial segment of the vertebral artery. There are many treatment options for symptomatic vertebral artery stenosis: secondary prevention with antiplatelet aggregation drugs alone, the annual stroke incidence rate is still as high as 15%; warfarin therapy is as effective as aspirin therapy, but the risk of bleeding is much lower increase; the surgical procedure is complicated, the risk is high, and its widespread clinical application is also limited. Vertebral artery stenosis has little effect on drug treatment, and the risk of surgery is too high and the limitations are too large. Endovascular treat...

Claims

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Application Information

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IPC IPC(8): A61F2/90A61L31/16A61M31/00
CPCA61F2/90A61F2240/001A61L31/16A61L2300/416A61L2300/604A61L2300/606A61M31/00A61M2210/12
Inventor 邹秋华于海瑞刘迎陈叶金巧蓉谢志永
Owner MICROPORT NEUROTECH SHANGHAI
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