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A kind of vaginal composition and the application of the composition

A composition and vaginal technology, applied in the field of medicine, can solve problems such as difficulty in meeting the needs of female vaginal hygiene, nursing, and health care, reduction in cure rate, and the like

Active Publication Date: 2020-04-17
SHENZHEN EULIKAN BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the international treatment of BV, metronidazole, an antibacterial drug with a strong effect on anaerobic bacteria, is the first choice, followed by clindamycin and other antibacterial drugs, but the cure rate of the two drugs is only about 60%, and the recurrence rate is as high as 30-40%. and the cure rate gradually decreased
Report by Livengood CH et al. in 2007 [10] According to the guidelines issued by the FDA in 1998, if the criteria of clinical cure and microbial cure are met at the same time, the cure rate of tinidazole in the treatment of BV is only 37%.
[0009] In view of the openness, fragility, and susceptibility of women's vaginas, as well as traditional vaginal douching, antibacterial drugs, and antibacterial products, it is difficult to meet the needs of women's vaginal hygiene, care, and health care, especially after menstruation, intercourse, and postmenopause. , and vaginal infection and other special physiological and pathological conditions, the need for vaginal hygiene, nursing, and health care, so the research and development of effective vaginal health products, health care products, hygiene products, medicines, etc., has become a urgent need of

Method used

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  • A kind of vaginal composition and the application of the composition
  • A kind of vaginal composition and the application of the composition
  • A kind of vaginal composition and the application of the composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] Prepare the composition as follows: Mix 9.0 grams of isomaltulose, 0.05 grams of sodium benzoate, 0.02 grams of sodium dehydroacetate, 0.5 grams of sodium propionate, and 2.7 grams of xanthan gum, add 100 milliliters of distilled water, stir and mix well , dissolving isomaltulose, sodium benzoate, sodium dehydroacetate and sodium propionate, xanthan gum swells into a uniform viscous colloid; adjust the pH to 5.0; sterilize at 112.6°C for 20 minutes to obtain the water-soluble Colloidal composition. Sterile, hermetically sealed sub-packaging by single dose, 5 grams per tube.

Embodiment 2

[0054] The raw materials were weighed according to the following proportions, and the composition was basically prepared according to the method of Example 1: 4.5 grams of isomaltulose, 0.02 grams of sodium dehydroacetate, 0.5 grams of sodium propionate, 2.5 mg of natamycin, xanthan Glue 2.6g, distilled water 100ml, pH 5.0, sterilized, single-dose sterile sealed packaging, 5.0g each.

Embodiment 3

[0056] The raw materials were weighed according to the following proportions, and the composition was basically prepared according to the method of Example 1: 12.0 grams of isomaltulose, 0.15 grams of sodium benzoate, 0.01 grams of sodium dehydroacetate, 0.5 grams of sodium propionate, 2.5 grams of xanthan gum grams, 100 ml of distilled water, pH 4.8.

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PUM

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Abstract

A use of isomaltulose in preparing a vaginal composition, wherein the amount of isomaltulose is 0.05-20w / w%. A composition for the vagina, which contains 0.05-20w / w% isomaltulose, and the composition can be a combination of health products, health care products, cleaning products, care products, deodorants, cosmetics, and disinfectants a method of non-therapeutic vaginal health care by administering said composition to a woman's vagina, and a method of non-therapeutic vaginal hygiene, and a method of enhancing vaginal acidity, and a method of promoting intravaginal A method for the growth of lactobacilli, and a method for the prevention and treatment of vaginal flora disorders, in particular bacterial vaginosis.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a vaginal composition, the use of the composition and a manufacturing method. Background technique [0002] The female vagina is an open system that is vulnerable to various microorganisms and pathogens. In a healthy state, beneficial lactobacilli live on the surface of the vaginal mucosa. Lactobacillus can metabolize the glycogen in the epithelial cells of the vaginal mucosa to produce acid, so that the acidity of the vagina can be kept in the range of pH 3.5-4.5, so that the vagina has a self-purification effect, which is an important part of the vagina's anti-infection ability. Once the acidity of the vagina weakens, it will affect the sanitation and health of the vagina and even the entire reproductive tract, bringing harm to women's lives. [0003] There are many types of Lactobacillus in the vagina, nearly 20 species can be detected [1] , Before 2000, it was considered ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7016A61P15/02
CPCA61K31/7016A61P15/02A61P31/02Y02A50/30A61K9/0034A61K9/06A61K31/565A61K36/886
Inventor 曾忠铭周汝云
Owner SHENZHEN EULIKAN BIOTECH CO LTD
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