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Dialysis membrane and method for its production

A technology of dialysis membrane and flat membrane, applied in dialysis system, semi-permeable membrane separation, chemical instruments and methods, etc., can solve the problem of reducing permeability

Inactive Publication Date: 2017-08-25
B BRAUN AVITUM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

When testing molecular weight cut-off values ​​with dextran, according to Kochan et al., a significant increase in dextran retention was observed in the coated membranes, however at the same time a decrease in permeability

Method used

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  • Dialysis membrane and method for its production
  • Dialysis membrane and method for its production
  • Dialysis membrane and method for its production

Examples

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Embodiment Construction

[0093] I. General description of the production of base films with different polymers.

[0094] A casting or spinning solution made of base film-polymer / additive / solvent is produced as follows: First, the selected additive and desired polymer / polymer blend are slowly dissolved in N,N-dimethyl Acetamide [DMAc] and appropriate amount of water (Solution 1).

[0095] The following compounds were used as membrane polymers: polysulfone [PSU] (M n 16-22kDa, M w 40-85kDa), sulfonated polysulfone [SPSU] (M w 50-55kDa, M n 27-32kDa), polyethersulfone [PES] (M w 30-75kDa, M n 16-22kDa), sulfonated polyethersulfone [SPES] (M w 30-35kDa, M n 18-22kDa), polyphenylsulfone [PPSU] (M w 52-55kDa, M n 22kDa), sulfonated polyphenylsulfone [SPPSU] (M w 47-53kDa, M n 17-21 kDa); and mixtures (blends) of these materials.

[0096] Modification of polymers PSU and PES was achieved by post-sulfonation. The polymer is dissolved in dichloromethane under inert gas (concentration 3...

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Abstract

A membrane for the purification of blood, or a dialysis membrane, in hollow-fiber membrane or flat membrane geometry, made of a composite assembled from at least a base membrane based on at least one polysulfone or a polyphenylsulfone with at least one pore-forming hydrophilic additive and at least one functional layer arranged on the base membrane, whereby the functional layer is formed from at least one polymeric polycationic bonding agent and at least one polymeric polyanion, whereby the base membrane is made of a material which is selected from: a polysulfone [PSU], a sulfonated polysulfone [SPSU], a polyethersulfone [PES], a sulfonated polyethersulfone [SPES], a polyphenylsulfone [PPSU], a sulfonated polyphenylsulfone [SPPSU]; and mixtures of these. The membranes according to the present invention exhibit high water permeability and low BSA sieving coefficients.

Description

technical field [0001] The invention concerns a dialysis membrane according to the preamble of claim 1 and a dialysis membrane according to claim 14 , a method for producing a dialysis membrane according to claim 9 , and a dialysis membrane module according to claim 15 . Background technique [0002] The following polymer abbreviations are used in the context of the present invention: [0003] abbreviation polymer DEXS Dextran Sulfate PA Polyamide PAAA Polyacrylic acid PAN Polyacrylonitrile PC polycarbonate PEG * polyethylene glycol PEI Polyethyleneimine PEOs * polyethylene oxide PES Polyphenylsulfone PMMA Polymethylmethacrylate PPSU Polyphenylsulfone PUR Polyurethane PSUs Polysulfone pvp Polyvinylpyrrolidone SPES Sulfonated polyethersulfone SPSU Sulfonated polysulfone SPPSU Sulfonated polyphenylsulfone [0004] * PEG and PEO are esse...

Claims

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Application Information

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IPC IPC(8): B01D71/68B01D69/08B01D69/06B01D67/00
CPCB01D67/0002B01D69/06B01D69/08B01D71/68B01D61/243B01D63/02B01D63/08B01D67/0009B01D69/02B01D69/10B01D2323/02B01D2325/36A61M1/16B01D69/12B01D2323/36B01D2325/14B01D2325/16B01D67/00046B01D69/1214B01D67/00B01D71/12B01D71/60B01D71/601B01D69/1216B01J41/13B01D67/0013B01D2325/04B32B27/286
Inventor 亚历山大·弗里贝罗兰·纳皮尔拉拉安吉拉·拜尔·戈许茨朱莉安·盖布勒马蒂亚斯·乌尔布莱特克莱利亚·杰德·埃莱奥诺雷·维多利亚·额敏
Owner B BRAUN AVITUM
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