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Method for simulating processing process of stir-fried medicinal materials

A processing technology and a technology for medicinal materials, which are applied in the field of simulating the processing technology of fried medicinal materials, can solve the problems of high frying temperature, can not well achieve processing to reduce toxicity, increase efficiency, and take a long time, and achieve accurate control of heating temperature, Accurately predict frying temperature and time, cost saving effect

Inactive Publication Date: 2017-09-01
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If the frying temperature is too high or too low, or the time is too long or too short, the purpose of detoxification and efficiency enhancement cannot be well achieved.

Method used

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  • Method for simulating processing process of stir-fried medicinal materials
  • Method for simulating processing process of stir-fried medicinal materials
  • Method for simulating processing process of stir-fried medicinal materials

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1 Study on Process Parameters of Aconitine Oil Bath Simulating Iron Rod and Hammer Sand Stir-fry

[0035] Taking aconitine, the main toxic component in the iron rod hammer, as the research object, the oil bath was used to simulate the sand frying process, and the conversion process was analyzed by HPLC; the content was determined by the external standard one-point method; It provides a basis for the quantitative standard research of sand frying process.

[0036] 1 Instruments and reagents

[0037] Agilent 1260 high performance liquid chromatograph, UV detector, Agilent Chemastation chromatographic workstation; CPA2250 electronic analytical balance (Germany Sartorius company); ULUP-I-10T Youpu ultrapure water machine (Chengdu Ultrapure Technology Co., Ltd.); HH- SJ heat-collecting magnetic stirrer (Jintan Chengdong Xinrui Instrument Factory); aconitine (Chengdu Master Biological Technology Co., Ltd., batch number MUST-15121111); acetonitrile is chromatographical...

Embodiment 2

[0052] Example 2 Using 3-acetylaconitine oil bath to simulate iron bar hammer sand frying process parameters

[0053] Taking 3-acetylaconitine, the main toxic component in iron bar hammer, as the research object, the oil bath was used to simulate the sand frying process, and the conversion process was analyzed by HPLC; the content was determined by the external standard one-point method; It provides a basis for the research on the quantitative standard of the hammer sand frying process.

[0054] 1 Instruments and reagents

[0055] Agilent 1260 high performance liquid chromatograph, UV detector, Agilent Chemastation chromatographic workstation; CPA2250 electronic analytical balance (Germany Sartorius company); ULUP-I-10T Youpu ultrapure water machine (Chengdu Ultrapure Technology Co., Ltd.); HH- SJ heat-collecting magnetic stirrer (Jintan Chengdong Xinrui Instrument Factory); 3-acetylaconitine (self-made, area normalization method, content> 98%); Methanol is chromatographicall...

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Abstract

The invention provides a method for simulating a processing process of stir-fried medicinal materials. The method comprises the following steps: a, selecting index components in medicinal materials; b, simulating stir-frying conditions by adopting an oil bath and uniformly adhering the index components to the bottom of a flask; c, detecting the content of the index components under different oil bath temperature and time conditions and analyzing detection results to obtain optimal stir-frying temperature and time of the medicinal materials. According to the method for simulating the processing process of the stir-fried medicinal materials, provided by the invention, conditions of a processing process of medicinal materials containing toxic alkaloids are especially screened and the stir-frying temperature and time of the medicinal materials can be accurately predicated under the condition that the medicinal materials are not used, so that the cost is saved and guarantees are provided for industrialized amplified processing.

Description

technical field [0001] The invention relates to a method for simulating the processing technology of roasted medicinal materials. Background technique [0002] Some traditional Chinese medicines and ethnic medicines must be processed before they can be used as medicines, which is one of the characteristics of traditional Chinese medicines and ethnic medicines. Traditional Chinese medicine processing is a pharmaceutical technology adopted according to the theory of traditional Chinese medicine, according to the needs of syndrome differentiation and treatment, the nature of the medicine itself, and the different requirements of dispensing and preparation. [0003] The processing of traditional Chinese medicine is a summary of the long-term clinical experience of traditional Chinese medicine. The determination of the processing technology should be based on clinical needs. Whether the processing technology is reasonable and the method is appropriate directly affects the clini...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/714
CPCA61K36/714A61K2236/17
Inventor 王毓杰康云雪孙海霞
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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