Composition for improving sleep and preparing method of composition

A technology for improving sleep and composition, applied in the field of composition for improving sleep and its preparation, can solve problems such as easy addiction, easy drug resistance, strong drug dependence, etc. control, non-toxic side effects

Inactive Publication Date: 2017-09-22
QINGHAI UNIV FOR NATITIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned drugs generally have defects such as strong drug dependence, easy addiction, and easy drug resistance.

Method used

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  • Composition for improving sleep and preparing method of composition
  • Composition for improving sleep and preparing method of composition
  • Composition for improving sleep and preparing method of composition

Examples

Experimental program
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Effect test

preparation example Construction

[0027] The present invention also provides a preparation method of the above composition. The first method is to mix the raw materials, preferably, the raw materials are pulverized and then mixed to form a powder of the composition. In this embodiment, there are many methods for obtaining the composition, such as extracting the raw materials with water, concentrating, drying, and mixing with pharmaceutical excipients to form granules, capsules, and tablets. It should be noted that the dosage form of the sleep-improving preparation provided in this example is not limited, and may also be a liquid or semi-solid preparation.

[0028] Another preparation method of the composition is also provided, using supercritical extraction of raw materials to obtain volatile oil and medicinal residues, wherein the extraction pressure is 25MPa-30MPa, the extraction temperature is 40-60°C, CO 2 The flow rate is 6-10kg / h, and the extraction time is 60-120min; the dregs are extracted with ethanol...

Embodiment 1

[0035] The present embodiment provides a composition for improving sleep, and its raw materials include: 20 parts by weight of nutmeg, 10 parts by weight of pepper (including black pepper and white pepper with a weight ratio of 0.8:1.5), 20 parts by weight of pepper fennel.

[0036] This embodiment provides a preparation method of the above composition for improving sleep, which includes: mixing raw materials.

Embodiment 2

[0038] The present embodiment provides a composition for improving sleep, and its raw materials include: 35 parts by weight of nutmeg, 25 parts by weight of pepper (including black pepper and white pepper with a weight ratio of 1:1), 40 parts by weight of pepper Fennel and cumin.

[0039] This embodiment provides the preparation method of the above sleep-improving composition, which includes: using supercritical extraction of raw materials to obtain volatile oil and medicinal residues, wherein the extraction pressure is 28 MPa, the extraction temperature is 40-60 ° C, CO 2 The flow rate is 7kg / h, and the extraction time is 80min; the medicinal dregs are used as 5 times of the medicinal dregs, and the concentration is 80% ethanol, and the extract is made after extraction for 45min at 55°C, and the volatile oil, extract and pharmaceutical excipients Mix and granulate.

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Abstract

The invention discloses a composition for improving sleep and a preparing method of the composition. The composition comprises, by weight, 20-35 parts of myristica fragrans, 10-25 parts of pepper, and at least one of 20-40 parts of fennel, carum carvi, and cumin cumin. The composition has an excellent effect in improving the sleep. The preparing method of the composition comprises the steps of adopting supercritical extraction on the raw materials to obtain volatile oil and drug residues, wherein the extraction pressure is 25MPa-30MPa, the extraction temperature is 40-60 DEG C, the CO2 flow is 6-10 kg / h, and the extraction time is 60-120 min. The drug residues are prepared into concrete through ethanol extraction, and the volatile oil, concrete and medicinal auxiliary materials are mixed to conduct pelletizing. The preparing method is simple, and the prepared composition is excellent in curative effect.

Description

technical field [0001] The invention relates to the technical field of medicine, and in particular to a composition for improving sleep and a preparation method thereof. Background technique [0002] With the accelerated pace of work and life, people's life and work pressure is increasing day by day. The resulting insomnia, depression and other problems have become a major problem that seriously endangers human health. According to the survey of the World Health Organization, about 27% of people have problems in varying degrees of sleep. In 2003, the statistics of 40,000 questionnaires from the China Sleep Research Association showed that as many as 38.2% of Chinese urban residents had different degrees of insomnia symptoms, which was higher than the ratio of 27% in the world. [0003] The drugs used to treat insomnia in modern medicine mainly include benzodiazepines and non-benzodiazepines, as well as other drugs that help sleep (including anti-anxiety drugs, antidepressa...

Claims

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Application Information

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IPC IPC(8): A61K36/67A61K9/16A61K47/69A61P25/20
CPCA61K9/1652A61K36/185A61K36/23A61K36/235A61K36/67A61K2236/333A61K2236/37A61K2300/00
Inventor 才让南加张金魁南杰东智左明丽林鹏程
Owner QINGHAI UNIV FOR NATITIES
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