Imaging reconstruction method and apparatus

Abstract

The invention provides an imaging reconstruction method and apparatus. The method comprises: a surface fluorescence image of an imaging region is obtained; according to the surface fluorescence image, a reconstruction equation is established based on a finite element method; a reconstruction objective function is constructed by using an elastic network penalty item coefficient and the reconstruction equation; and on the basis of a near-end gradient method, iterative solution is carried out on reconstruction objective function to generate an imaging reconstruction result. With the surface fluorescence signal, balancing between sparsity and smoothness of the reconstruction target is realized by the elastic network penalty item; and on the basis of the near-end gradient lgorithm, the equation is solved to obtain a fluorescent light distribution component rapidly, so that a light source distribution image is constructed rapidly and precisely. Therefore, the reconstruction time is reduced; the resolution is improved; and the equipment hardware cost is lowered.

Description

technical field [0001] The invention relates to image processing technology, in particular to an imaging reconstruction method and device. Background technique [0002] Molecular imaging technology is a highly sensitive biomedical imaging technology newly developed in recent years. It can perform non-invasive imaging of organisms at the cellular and molecular levels, which is conducive to the study of changes in the molecular level of organisms. It has been widely used in research and development and has achieved rapid development. [0003] Optical molecular imaging is a kind of molecular imaging technology. Optical molecular imaging uses an external light source to excite fluorescent markers in organisms, and the excited fluorescent markers emit fluorescence in the near-infrared band, and use high-sensitivity detectors to receive fluorescent information. And form a fluorescent image. There is no radioactive risk in the imaging process. Compared with other imaging modaliti...

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the shortcomings of the existing fluorescence image reconstruction technology, solve the problem of inaccurate imaging and slow imaging speed in the existing optical molecular imaging system, in order to reconstruct the fluorescence distribution image efficiently and accurately, provide a fast molecular and cellular level Accurate imaging, the present invention provides an imaging reconstruction method, comprising:

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