Check patentability & draft patents in minutes with Patsnap Eureka AI!

The medicinal application of rhodiola grandiflorum

A technology of Rhodiola grandiflora and medicine, which is applied in the field of medicine and can solve problems such as teratogenicity and carcinogenicity

Active Publication Date: 2020-02-18
SHANGHAI UNIV OF T C M
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are also very strict requirements on the dosage of polyphenolic compounds such as kojic acid and ursolic acid. Excessive doses can also cause carcinogenic, teratogenic and other toxic side effects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • The medicinal application of rhodiola grandiflorum
  • The medicinal application of rhodiola grandiflorum
  • The medicinal application of rhodiola grandiflorum

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0012] The advent of the present invention is based on the unexpected discovery that the flavonoid Rhodiola macrophylla has a good inhibitory effect on tyrosinase activity both in vivo and in vitro. Therefore, Rhodiola rosea is expected to be developed as a drug or cosmetic that inhibits tyrosinase activity.

[0013] As used in the present invention, the compound of the present invention Rhodiola rosea, its molecular formula: C 25 H 20 O 10 , Molecular weight: 480.11, its structural formula is as follows:

[0014]

[0015] As known to those of ordinary skill in the art, the compound of the present invention Rhodiola crenulata can be purchased commercially, and can also be obtained from Rhodiola crenulata (scientific name: Rhodiola crenulata (HK. f.et.Thoms)H.Ohba) and so on. Its purity meets the medical standards.

[0016] The rhodiola macrophylla of the present invention can be used alone or in the form of a pharmaceutical composition. The pharmaceutical composition includes the ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the field of medicines, and particularly relates to medicinal application of rhodiolinin. The rhodiolinin can be used for preparing medicines, health products and cosmetics for inhibiting tyrosinase activity.

Description

Technical field [0001] The present invention relates to the field of medicine, in particular to the use of flavonoids and related products. Background technique [0002] Pigmentation is caused by excessive accumulation of melanin. The main clinical manifestations are skin problems and diseases such as freckles, brown spots and even melanoma. [0003] At present, it is generally believed that the synthesis pathway of melanin is: tyrosine produces dopa under the action of tyrosinase, dopa produces dopaquinone under the action of tyrosinase, dopaquinone forms dopachrome, and dopachrome forms dihydroxyl Indole and dihydroxyindole are oxidized to form ketoindole, and finally ketoindole is polymerized to eumelanin. In this reaction pathway, dopaquinone can also be catalyzed by glutathionase or cysteinase to produce pheomelanin. Eumelanin and pheomelanin form melanin, and eumelanin is the main skin pigment. Component, the effect of pheomelanin in the skin is currently unclear. [0004] ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/357A61P17/00A61K8/49A61Q19/02
CPCA61K8/498A61K31/357A61K2800/782A61Q19/02
Inventor 吴弢周金阁孔瑶施继尧张娜
Owner SHANGHAI UNIV OF T C M
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com