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Skin-whitening and brightening composition and preparation method and application thereof

A composition and skin-lightening technology, applied in the directions of skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve problems such as unsatisfactory permeability, hydroquinone photophobia, cytotoxic reaction, etc., and achieve convenient industrial production. Effect of application, inhibition of synthesis, high skin whitening activity

Inactive Publication Date: 2018-01-19
中山市汉宸生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Excessive use of hydroquinone can cause cytotoxic reactions; and hydroquinone is very sensitive to light, and the product is easy to change color and deteriorate. burden
In addition, the active substances of arbutin, licorice flavonoids, retinoic acid, fruit acid and azelaic acid have unsatisfactory permeability, making these whitening products less effective

Method used

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  • Skin-whitening and brightening composition and preparation method and application thereof
  • Skin-whitening and brightening composition and preparation method and application thereof
  • Skin-whitening and brightening composition and preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 3

[0045] Taking Example 3 as an example, the preparation process is as follows:

[0046] (1) Weigh hydrolyzed yeast protein, sweet orange extract, rice extract, caper fruit extract, olive leaf extract, nicotinamide, 1,2-hexanediol, 1,2-octyl Glycol, 1,2-pentanediol, triethanolamine, glycerol and water;

[0047] (2) First prepare the composite polyol antibacterial agent, and stir 1,2-hexanediol, 1,2-octanediol, and 1,2-pentanediol evenly to prepare the composite polyol antibacterial agent for future use;

[0048] (3) Add water to glycerol, stir to obtain solvent;

[0049] (4) Add the rice extract of the formulated amount into the solvent, stir and heat to 50-60°C until completely dissolved;

[0050] (5) After step (4) is completely dissolved, stir and cool to 40-45°C, add sweet orange extract, caper fruit extract, olive leaf extract, nicotinamide, compound polyol antibacterial agent and triethanolamine to mix, Set the stirring rate to 18rpm / min, and keep stirring for 20 minute...

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Abstract

The invention relates to a skin-whitening and brightening composition and a preparation method and an application thereof. The skin-whitening and brightening composition comprises the following components in parts by weight: 1 part of a skin-whitening and brightening active ingredient composition, 10-15 parts of a solvent, 0.05-0.15 parts of a composite polyol antiseptic, and 0.05-0.15 parts of apH stabilizing agent. The invention also provides the preparation method and the application of the skin-whitening and brightening composition. The skin-whitening and brightening composition has whitening effect, can obviously reduce the melanin generation, and has no photoactivate effect, after the skin-whitening and brightening composition is added in a formula, a shading component is not required, and the skin-whitening and brightening composition has good skin survivability and high safety, and has the advantages of no toxicity and no stimulation on human body. In addition, the preparationmethod of the composition is easily operated and is convenient for industrial production application.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a composition for whitening and brightening skin, a preparation method and application thereof. Background technique [0002] When people's skin is irradiated by ultraviolet rays, it will produce and release melanin, which determines the color of human skin, causing darkening of the skin, and even hyperpigmentation, such as melasma, freckles and spots, all of which have adverse effects on beauty. influences. The synthesis process of melanin is as follows: tyrosinase in cells acts on tyrosine to form dopaquinone, thereby producing melanin. Therefore, in order to prevent darkening of the skin, researchers have devoted themselves to studying the inhibition of part of the synthesis process of melanin, thereby reducing the synthesis of melanin itself. [0003] At present, the general skin whitening agent is to reduce the production of melanin by inhibiting the activity of tyrosinase or bloc...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/9789A61K8/67A61K8/64A61Q19/02
Inventor 兰永忠李锦明许红军陈活明刘刚
Owner 中山市汉宸生物科技有限公司
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